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Details

Stereochemistry ACHIRAL
Molecular Formula C21H17F2N5O3S
Molecular Weight 457.453
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Darizmetinib

SMILES

CCCS(=O)(=O)NC1=C(F)C=CC(C(=O)C2=NNC3=NC=C(C=C23)C4=CC=NC=C4)=C1F

InChI

InChIKey=WBNMARNYIFMNEP-UHFFFAOYSA-N
InChI=1S/C21H17F2N5O3S/c1-2-9-32(30,31)28-19-16(22)4-3-14(17(19)23)20(29)18-15-10-13(11-25-21(15)27-26-18)12-5-7-24-8-6-12/h3-8,10-11,28H,2,9H2,1H3,(H,25,26,27)

HIDE SMILES / InChI

Molecular Formula C21H17F2N5O3S
Molecular Weight 457.453
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Fri Jul 07 00:56:11 UTC 2023
Edited
by admin
on Fri Jul 07 00:56:11 UTC 2023
Record UNII
Q2HX6A3UDW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Darizmetinib
INN  
Official Name English
N-{2,6-difluoro-3-[5-(pyridin-4-yl)-1H-pyrazolo[3,4- b]pyridine-3-carbonyl]phenyl}propane-1-sulfonamide
Systematic Name English
1-Propanesulfonamide, N-[2,6-difluoro-3-[[5-(4-pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]carbonyl]phenyl]-
Systematic Name English
darizmetinib [INN]
Common Name English
N-[2,6-Difluoro-3-[[5-(4-pyridinyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]carbonyl]phenyl]-1-propanesulfonamide
Systematic Name English
Code System Code Type Description
INN
12490
Created by admin on Fri Jul 07 00:56:11 UTC 2023 , Edited by admin on Fri Jul 07 00:56:11 UTC 2023
PRIMARY
CAS
2369583-33-3
Created by admin on Fri Jul 07 00:56:11 UTC 2023 , Edited by admin on Fri Jul 07 00:56:11 UTC 2023
PRIMARY
NCI_THESAURUS
C199030
Created by admin on Fri Jul 07 00:56:11 UTC 2023 , Edited by admin on Fri Jul 07 00:56:11 UTC 2023
PRIMARY
FDA UNII
Q2HX6A3UDW
Created by admin on Fri Jul 07 00:56:11 UTC 2023 , Edited by admin on Fri Jul 07 00:56:11 UTC 2023
PRIMARY
PUBCHEM
139369660
Created by admin on Fri Jul 07 00:56:11 UTC 2023 , Edited by admin on Fri Jul 07 00:56:11 UTC 2023
PRIMARY