Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C10H13O.K |
| Molecular Weight | 188.3079 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[K+].CC(C)(C)C1=CC=C([O-])C=C1
InChI
InChIKey=YPPBVACKXHPUGV-UHFFFAOYSA-M
InChI=1S/C10H14O.K/c1-10(2,3)8-4-6-9(11)7-5-8;/h4-7,11H,1-3H3;/q;+1/p-1
| Molecular Formula | K |
| Molecular Weight | 39.0983 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C10H13O |
| Molecular Weight | 149.2096 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
The main use of p-tert-butylphenol (P.T.B.P.) is the
production of resins for adhesives used in the car industry.
It is a white crystalline solid which melts at
97-98 oC to a clear, colourless liquid, and vaporises at
260 oC. It has being shown that occupational exposure to p-tert-butylphenol (ptBP) leads to vitiligo. Aminopyrine demethylase inhibitor.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Do commercially available metal salts mediate calixarene formation via hydrogen-bonded dimers? | 2011-09-02 |
|
| Dirhodium-catalyzed phenol and aniline oxidations with T-HYDRO. Substrate scope and mechanism of oxidation. | 2011-04-15 |
|
| [Induction of occupational leucoderma and vitiligo. Can butylated hydroxytoluene induce vitiligo similarly to p-tert-butylphenol?]. | 2011-03 |
|
| Synthesis of diazacalix[8]arene and triazacalix[12]arene methyl ethers via intramolecular aryl amination. | 2009-02-19 |
|
| Azolium-linked cyclophanes: a comprehensive examination of conformations by 1H NMR spectroscopy and structural studies. | 2004-10-29 |
|
| Occupational vitiligo induced by p-tert-butylphenol, a systemic disease? | 1977-12-10 |
Patents
Sample Use Guides
In Vivo Use Guide
Curator's Comment: Rats: Aminopyrine demethylase activity was inhibited by the administration of p-tert-butylphenol at a dose of 2 and 10 mg/kg, p.o.
https://www.ncbi.nlm.nih.gov/pubmed/3172284
Rats: Following intravenous injection of 14C-p-tert-butylphenol (14C-TB, 50 umol/kg) with PPBA (50 umol/kg), the sulfation of 14C-TB was decreased by 38.8% and its glucuronidation increased by 62.3%.
Route of Administration:
Intravenous
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:49:48 GMT 2025
by
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on
Mon Mar 31 21:49:48 GMT 2025
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| Record UNII |
Q29F3DF6CT
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| Record Status |
Validated (UNII)
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EPA PESTICIDE CODE |
64114
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