MT-45

C(C(N1CCN(CC1)C2CCCCC2)C3=CC=CC=C3)C4=CC=CC=C4

InChIKey=IGBRRSIHEGCUEN-UHFFFAOYSA-N

InChI=1S/C24H32N2/c1-4-10-21(11-5-1)20-24(22-12-6-2-7-13-22)26-18-16-25(17-19-26)23-14-8-3-9-15-23/h1-2,4-7,10-13,23-24H,3,8-9,14-20H2

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Targets

Primary Target	Pharmacology	Potency
Mu opioid receptor 221 Target ID: CHEMBL233 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29973882	Agonist 2678	44.0 nM [Ki]
Delta opioid receptor 77 Target ID: CHEMBL236 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29973882	Agonist 2678	606.0 nM [Ki]
Kappa opioid receptor 108 Target ID: CHEMBL237 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29973882	Agonist 2678	204.0 nM [Ki]

PubMed

Title	Date	PubMed
Chondrocyte-derived ezrin-like domain containing protein (CDEP), a rho guanine nucleotide exchange factor, is inducible in chondrocytes by parathyroid hormone and cyclic AMP and has transforming activity in NIH3T3 cells.	2001	11680691

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:16:51 GMT 2023` Edited by `admin` on `Sat Dec 16 02:16:51 GMT 2023`
Record UNII	Q2640DPW33
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

MT-45

Common Name

English

MT 45 [WHO-DD]

Common Name

English

1- CYCLOHEXYL-4-(1,2-DIPHENYLETHYL)PIPERAZINE

Systematic Name

English

IC-6

Code

English

PIPERAZINE, 1-CYCLOHEXYL-4-(1,2-DIPHENYLETHYL)-

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA