METHAPHENILENE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H20N2S
Molecular Weight	260.398
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METHAPHENILENE

Structure Search

SMILES

CN(C)CCN(CC1=CC=CS1)C2=CC=CC=C2

InChI

InChIKey=LDYJXVUOVPVZKA-UHFFFAOYSA-N

InChI=1S/C15H20N2S/c1-16(2)10-11-17(13-15-9-6-12-18-15)14-7-4-3-5-8-14/h3-9,12H,10-11,13H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C15H20N2S
Molecular Weight	260.398
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6847382

Methaphenilene, an antihistaminic agent, was studied as a peroxisome proliferator. Information about the current use of this compound is not available.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Methaphenilene, an analogue of the antihistaminic methapyrilene, is a "peroxisome proliferator".	1983-02	6847382
NEW and nonofficial remedies: methaphenilene hydrochloride.	1951-10-27	14873577
Agranulocytosis during therapy with the antihistaminic agent methaphenilene.	1950-02-18	15402390

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:15:58 GMT 2025` Edited by `admin` on `Mon Mar 31 18:15:58 GMT 2025`
Record UNII	Q1MP2MRW1E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METHAPHENILENE [MI]

Preferred Name

English

METHAPHENILENE

Official Name

English

1,2-ETHANEDIAMINE, N,N-DIMETHYL-N'-PHENYL-N'-(2-THIENYLMETHYL)-

Systematic Name

English

ETHYLENEDIAMINE, N,N-DIMETHYL-N'-PHENYL-N'-2-THENYL-

Systematic Name

English

N,N-DIMETHYL-N'-(.ALPHA.-THENYL)-N'-PHENETHYLENEDIAMINE

Common Name

English

methaphenilene [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29578

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

Code System Code Type Description

INN

1880

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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ChEMBL

CHEMBL2111026

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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ECHA (EC/EINECS)

207-780-3

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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CAS

493-78-7

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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EPA CompTox

DTXSID5020817

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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PUBCHEM

10306

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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FDA UNII

Q1MP2MRW1E

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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WIKIPEDIA

Methaphenilene

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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SMS_ID

100000081227

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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DRUG CENTRAL

1737

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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EVMPD

SUB08838MIG

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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MESH

C037531

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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NCI_THESAURUS

C83952

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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MERCK INDEX

m327

Created by admin on Mon Mar 31 18:15:58 GMT 2025 , Edited by admin on Mon Mar 31 18:15:58 GMT 2025

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Merck Index

Related Record Type Details


					DK0OIL461Z

METHAPHENILENE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					Q1MP2MRW1E

ACTIVE MOIETY