MIRAVIRSEN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Sat Dec 16 09:19:24 UTC 2023` Edited by `admin` on `Sat Dec 16 09:19:24 UTC 2023`
Nucleic Acid Subtype
Sequence Type	OLIGONUCLEOTIDE
Record UNII	Q083AJW7VS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MIRAVIRSEN

Official Name

English

Miravirsen [WHO-DD]

Common Name

English

SPC-3649

Code

English

SPC3649

Code

English

RNA, (P-THIO)((2'-O,4'-C-METHYLENE)M5C-DC-(2'-O,4'-C-METHYLENE)A-DT-DT-(2'-O,4'-C-METHYLENE)G-(2'-O,4'-C-METHYLENE)M5U-DC-DA-(2'-O,4'-C-METHYLENE)M5C-DA-(2'-O,4'-C-METHYLENE)M5C-DT-(2'-O,4'-C-METHYLENE)M5C-(2'-O,4'-C-METHYLENE)M5C)

Common Name

English

miravirsen [INN]

Common Name

English

Code System Code Type Description

FDA UNII

Q083AJW7VS

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

INN

9168

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

CAS

1072874-90-8

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

NCI_THESAURUS

C174858

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

DRUG BANK

DB12851

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

PUBCHEM

56843415

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

WIKIPEDIA

Miravirsen

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

ChEMBL

CHEMBL2108360

Created by admin on Sat Dec 16 09:19:24 UTC 2023 , Edited by admin on Sat Dec 16 09:19:24 UTC 2023

PRIMARY

Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_2;1_4-1_5;1_8-1_9;1_11;1_13	7 / 15
2'-O-Methyl-Ribose	1_1;1_3;1_6-1_7;1_10;1_12;1_14-1_15	8 / 15

Linkage	Site Range	Site Count
Phosporothioate	1_2-1_15	14 / 14

Related Record Type Details


					9ER39U6GCI

MIRAVIRSEN SODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					Q083AJW7VS

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
BASE SUBSTITUTION	[1_1] [1_9] [1_12] [1_14] [1_15]		CYTOSINE		5-METHYLCYTOSINE	6R795CQT4H