NICOFIBRATE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H16ClNO3.ClH
Molecular Weight	342.217
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(C)(OC1=CC=C(Cl)C=C1)C(=O)OCC2=CC=CN=C2

InChI

InChIKey=MTTOJXKYQMOKBL-UHFFFAOYSA-N

InChI=1S/C16H16ClNO3.ClH/c1-16(2,21-14-7-5-13(17)6-8-14)15(19)20-11-12-4-3-9-18-10-12;/h3-10H,11H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C16H16ClNO3
Molecular Weight	305.756
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/323747 | https://www.drugfuture.com/chemdata/nicofibrate.html

Nicofibrate is an antilipidemic drug. Treatment of diabetics led to a significant reduction in plasma cholesterol and triglycerides and brought the lipoprotein picture back within the norm. Nicofibrate did not lead to significant increases in uricaemia nor to any worsening in carbohydrate tolerance. Nicofibrate may also lead to a significant drop in plasma prothrombinic activity.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Therapeutic effects of nicofibrate on diabetic hyperlipemia].	1977-04-21	323747

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:41:28 GMT 2025` Edited by `admin` on `Mon Mar 31 22:41:28 GMT 2025`
Record UNII	PZE81ZT0MP
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NICOFIBRATE HYDROCHLORIDE

Common Name

English

ARTERIUM V

Preferred Name

English

NICOFIBRATE HYDROCHLORIDE [MI]

Common Name

English

PROPANOIC ACID, 2-(4-CHLOROPHENOXY)-2-METHYL-, 3-PYRIDINYLMETHYL ESTER, HYDROCHLORIDE (1:1)

Common Name

English

Code System Code Type Description

EPA CompTox

DTXSID60938471