CAPSIATE

COC1=CC(COC(=O)CCCC\C=C\C(C)C)=CC=C1O

InChIKey=ZICNYIDDNJYKCP-SOFGYWHQSA-N

InChI=1S/C18H26O4/c1-14(2)8-6-4-5-7-9-18(20)22-13-15-10-11-16(19)17(12-15)21-3/h6,8,10-12,14,19H,4-5,7,9,13H2,1-3H3/b8-6+

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

PubMed

Title	Date	PubMed
Immunosuppressive activity of capsaicinoids: capsiate derived from sweet peppers inhibits NF-kappaB activation and is a potent antiinflammatory compound in vivo.	2002 Jun	12115659
Effect of topical application of capsaicin and its related compounds on dermal insulin-like growth factor-I levels in mice and on facial skin elasticity in humans.	2007 Apr	17307377
Downregulation of uncoupling protein-3 in vivo is linked to changes in muscle mitochondrial energy metabolism as a result of capsiate administration.	2007 May	17264228
Capsiate, a nonpungent capsaicin-like compound, inhibits angiogenesis and vascular permeability via a direct inhibition of Src kinase activity.	2008 Jan 1	18172315

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:27:51 GMT 2023` Edited by `admin` on `Sat Dec 16 02:27:51 GMT 2023`
Record UNII	PX8I7HG5I3
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

CAPSIATE

Common Name

English

6-NONENOIC ACID, 8-METHYL-, (4-HYDROXY-3-METHOXYPHENYL)METHYL ESTER, (6E)-

Common Name

English

Code System Code Type Description

CAS

205687-01-0

Created by admin on Sat Dec 16 02:27:51 GMT 2023 , Edited by admin on Sat Dec 16 02:27:51 GMT 2023

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FDA UNII

PX8I7HG5I3

Created by admin on Sat Dec 16 02:27:51 GMT 2023 , Edited by admin on Sat Dec 16 02:27:51 GMT 2023

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EPA CompTox

DTXSID20174575

Created by admin on Sat Dec 16 02:27:51 GMT 2023 , Edited by admin on Sat Dec 16 02:27:51 GMT 2023

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PUBCHEM

9839519

Created by admin on Sat Dec 16 02:27:51 GMT 2023 , Edited by admin on Sat Dec 16 02:27:51 GMT 2023

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