NORTETRAZEPAM

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H15ClN2O
Molecular Weight	274.745
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NORTETRAZEPAM

Structure Search

SMILES

ClC1=CC2=C(NC(=O)CN=C2C3=CCCCC3)C=C1

InChI

InChIKey=FDRMSENAXZDFTN-UHFFFAOYSA-N

InChI=1S/C15H15ClN2O/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h4,6-8H,1-3,5,9H2,(H,18,19)

HIDE SMILES / InChI

Molecular Formula	C15H15ClN2O
Molecular Weight	274.745
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf?sequence=1&isAllowed=y | https://www.ncbi.nlm.nih.gov/pubmed/6148954 | https://books.google.ru/books?id=PQwlBQAAQBAJ&pg=PA11&lpg=PA11&dq=NORTETRAZEPAM retrieved from Drug Design: Medicinal Chemistry: A Series of Monographs, Volume 6 edited by E. J. Ariëns, p.11

Nortetrazepam is a benzodiazepine derivative, it is one of the major metabolites of tetrazepam. Nortetrazepam is a psychosedative agent.

Approval Year

PubMed

PubMed

Title	Date	PubMed
A spectrophotometric and polarographic investigation of three new cyclohexene-substituted benzodiazepines.	1978 Apr	18962241
Biotransformation and pharmacokinetics of tetrazepam in man.	1984	6148954

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:26:09 GMT 2025` Edited by `admin` on `Mon Mar 31 18:26:09 GMT 2025`
Record UNII	PWL441R6EQ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CB 4260

Preferred Name

English

NORTETRAZEPAM

Official Name

English

7-CHLORO-5-(1-CYCLOHEXEN-1-YL)-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE

Systematic Name

English

nortetrazepam [INN]

Common Name

English

TETRAZEPAM IMPURITY E [EP IMPURITY]

Common Name

English

CB-4260

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C1012

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

Code System Code Type Description

ChEMBL

CHEMBL2105147

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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INN

2573

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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SMS_ID

100000083602

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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EPA CompTox

DTXSID40146057

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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NCI_THESAURUS

C76537

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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FDA UNII

PWL441R6EQ

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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EVMPD

SUB09379MIG

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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PUBCHEM

166581

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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WIKIPEDIA

NORTETRAZEPAM

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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CAS

10379-11-0

Created by admin on Mon Mar 31 18:26:09 GMT 2025 , Edited by admin on Mon Mar 31 18:26:09 GMT 2025

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PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					PWL441R6EQ

ACTIVE MOIETY