Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H16N2.ClH |
| Molecular Weight | 224.73 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CN(C)CCC1=CNC2=CC=CC=C12
InChI
InChIKey=FXCHKLOHTIIVJW-UHFFFAOYSA-N
InChI=1S/C12H16N2.ClH/c1-14(2)8-7-10-9-13-12-6-4-3-5-11(10)12;/h3-6,9,13H,7-8H2,1-2H3;1H
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C12H16N2 |
| Molecular Weight | 188.2688 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A proposed mechanism for the visions of dream sleep. | 1988 Jun |
|
| Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects. | 1994 Feb |
|
| [Antimycobacterial indole derivatives]. | 1994 Feb |
|
| Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan. | 1996 Dec |
|
| Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor. | 1996 Jan |
|
| Psychedelic effects of ketamine in healthy volunteers: relationship to steady-state plasma concentrations. | 1998 Jan |
|
| Urinary excretion of dietary contaminants in horses. | 2006 Aug |
|
| The mysterious trace amines: protean neuromodulators of synaptic transmission in mammalian brain. | 2006 Aug |
|
| The adverse effects of hallucinogens from intramural perspective. | 2006 Dec |
|
| Detection and determination of abused hallucinogens in biological material. | 2006 Dec |
|
| Increased frontal and paralimbic activation following ayahuasca, the pan-Amazonian inebriant. | 2006 May |
|
| Not imagining it. Research into hallucinogens cautiously resumes. | 2006 Nov |
|
| NMR spectral assignments of a new chlorotryptamine alkaloid and its analogues from Acacia confusa. | 2007 Apr |
|
| DMT at fifty. | 2007 Dec |
|
| A quantitative synthesis of the medicinal ethnobotany of the Malinké of Mali and the Asháninka of Peru, with a new theoretical framework. | 2007 Dec 5 |
|
| Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids. | 2007 Jan |
|
| Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members. | 2007 Jul 25 |
|
| Further studies on the binding of N1-substituted tryptamines at h5-HT6 receptors. | 2007 Mar 15 |
|
| Prepulse inhibition of the startle reflex and its attentional modulation in the human S-ketamine and N,N-dimethyltryptamine (DMT) models of psychosis. | 2007 May |
|
| Daytime Ayahuasca administration modulates REM and slow-wave sleep in healthy volunteers. | 2008 Feb |
|
| Comparison of the separation of nine tryptamine standards based on gas chromatography, high performance liquid chromatography and capillary electrophoresis methods. | 2008 Feb 15 |
|
| A general approach to the screening and confirmation of tryptamines and phenethylamines by mass spectral fragmentation. | 2008 Jan 15 |
|
| The "vine of the soul" vs. the Controlled Substances Act: implications of the hoasca case. | 2008 Jun |
|
| [Inhibition of return in schizophrenia: a review]. | 2008 Jun |
|
| N,N-Dimethyltryptamine and dichloromethane: rearrangement of quaternary ammonium salt product during GC-EI and CI-MS-MS analysis. | 2008 May 12 |
|
| Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors. | 2008 Nov |
|
| Reassessing the cultural and psychopharmacological significance of Banisteriopsis caapi: preparation, classification and use among the Piaroa of Southern Venezuela. | 2008 Sep |
|
| Serotonin 5-HT(2A) Receptor Function as a Contributing Factor to Both Neuropsychiatric and Cardiovascular Diseases. | 2009 |
|
| A multi-component LC-MS/MS method for detection of ten plant-derived psychoactive substances in urine. | 2009 Apr 15 |
|
| Characterisation of a proposed internet synthesis of N,N-dimethyltryptamine using liquid chromatography/electrospray ionisation tandem mass spectrometry. | 2009 Aug 14 |
|
| Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter. | 2009 Dec |
|
| Optimization of separation and online sample concentration of N,N-dimethyltryptamine and related compounds using MEKC. | 2009 Feb |
|
| The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator. | 2009 Feb 13 |
|
| Bioanalytical and clinical evaluation of 103 suspected cases of intoxications with psychoactive plant materials. | 2009 Jul |
|
| Comparison of the discriminative stimulus effects of dimethyltryptamine with different classes of psychoactive compounds in rats. | 2009 Jul |
|
| When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor. | 2009 Mar 10 |
|
| Gas chromatographic analysis of dimethyltryptamine and beta-carboline alkaloids in ayahuasca, an Amazonian psychoactive plant beverage. | 2009 Mar-Apr |
|
| Predicting new molecular targets for known drugs. | 2009 Nov 12 |
|
| The neural correlates of religious and nonreligious belief. | 2009 Oct 1 |
|
| Sigma receptors in oncology: therapeutic and diagnostic applications of sigma ligands. | 2010 |
|
| Psychometric evaluation of the altered states of consciousness rating scale (OAV). | 2010 Aug 31 |
|
| The chemical basis of pharmacology. | 2010 Dec 7 |
|
| Antioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts. | 2010 Jan 22 |
|
| Characterization of the synthesis of N,N-dimethyltryptamine by reductive amination using gas chromatography ion trap mass spectrometry. | 2010 Jul |
|
| Alkaloids from Fissistigma latifolium (Dunal) Merr. | 2010 Jun 24 |
|
| Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management. | 2010 Jun 24 |
|
| Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population. | 2010 Mar |
|
| Neuronal correlates of visual and auditory alertness in the DMT and ketamine model of psychosis. | 2010 Oct |
|
| Dimethyltryptamine (DMT): subjective effects and patterns of use among Australian recreational users. | 2010 Sep 1 |
|
| The hallucinogenic world of tryptamines: an updated review. | 2015 Aug |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 16 16:52:50 UTC 2022
by
admin
on
Fri Dec 16 16:52:50 UTC 2022
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| Record UNII |
PRC2H3HFU4
|
| Record Status |
Validated (UNII)
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| Record Version |
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PRC2H3HFU4
Created by
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2826-93-9
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PD 004
Created by
admin on Fri Dec 16 16:52:50 UTC 2022 , Edited by admin on Fri Dec 16 16:52:50 UTC 2022
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25944
Created by
admin on Fri Dec 16 16:52:50 UTC 2022 , Edited by admin on Fri Dec 16 16:52:50 UTC 2022
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |
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