COSIBELIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:20:11 GMT 2023` Edited by `admin` on `Sat Dec 16 14:20:11 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	PNW7GBB44P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CK-301

Preferred Name

English

COSIBELIMAB

Official Name

English

ANTI-PD-L1 MONOCLONAL ANTIBODY CK-301

Common Name

English

cosibelimab [INN]

Common Name

English

TG-1501

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN PROGRAMMED DEATH-LIGAND 1) (HUMAN MONOCLONAL CK-301 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CK-301 .LAMBDA.-CHAIN, DIMER

Common Name

English

IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS PROGRAMMED CELL DEATH 1 LIGAND 1 (PD-L1, CD274 ANTIGEN))HUMAN MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (HOMO SAPIENS VH (IGHV1-69*01 (94%) (IGHD)-IGHJ1*01) (8.8.13) (1-120)-HOMO SAPIENS IGHG1*01 (121-45

Common Name

English

COSIBELIMAB [USAN]

Common Name

English

Cosibelimab [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C128057

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

NCI_THESAURUS

C129822

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

Code System Code Type Description

CAS

2216751-26-5

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

PRIMARY

INN

11107

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

PRIMARY

FDA UNII

PNW7GBB44P

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

PRIMARY

USAN

HI-183

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

PRIMARY

NCI_THESAURUS

C151947

Created by admin on Sat Dec 16 14:20:11 GMT 2023 , Edited by admin on Sat Dec 16 14:20:11 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_147	2_203
2_223	4_217
2_264	2_324
1_147	1_203
2_370	2_428
3_22	3_91
3_140	3_199
4_22	4_91
4_140	4_199
1_223	3_217
1_229	2_229
1_232	2_232
1_264	1_324
1_370	1_428

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_300
N	2_300

Related Record Type Details


					L4766ELH5T

PROGRAMMED CELL DEATH 1 LIGAND 1

TARGET -> INHIBITOR

Related Record Type Details


					PNW7GBB44P

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL