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Details

Stereochemistry ACHIRAL
Molecular Formula C15H10O5
Molecular Weight 270.2369
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 4',6,7-TRIHYDROXYISOFLAVONE

SMILES

OC1=CC=C(C=C1)C2=COC3=C(C=C(O)C(O)=C3)C2=O

InChI

InChIKey=GYLUFQJZYAJQDI-UHFFFAOYSA-N
InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-14-6-13(18)12(17)5-10(14)15(11)19/h1-7,16-18H

HIDE SMILES / InChI

Molecular Formula C15H10O5
Molecular Weight 270.2369
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
[Chemical constituents of bear bile].
2010-09
Potential health-modulating effects of isoflavones and metabolites via activation of PPAR and AhR.
2010-03
Red clover extract: a source for substances that activate peroxisome proliferator-activated receptor alpha and ameliorate the cytokine secretion profile of lipopolysaccharide-stimulated macrophages.
2010-03
Natural ortho-dihydroxyisoflavone derivatives from aged Korean fermented soybean paste as potent tyrosinase and melanin formation inhibitors.
2010-02-01
A-ring ortho-specific monohydroxylation of daidzein by cytochrome P450s of Nocardia farcinica IFM10152.
2009-11
Inhibitory effect of flavonoids on 26S proteasome activity.
2009-10-28
Isolation of a new metabolite from biotransformation of daidzein by Aspergillus oryzae.
2009-08
An updated review of tyrosinase inhibitors.
2009-05-26
Receptor binding and transactivation activities of red clover isoflavones and their metabolites.
2008-11
ortho-dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity.
2008-09-15
Red clover extract: a putative source for simultaneous treatment of menopausal disorders and the metabolic syndrome.
2008-08-30
Estrogenic activities of isoflavones and flavones and their structure-activity relationships.
2008-01
In vitro and in vivo metabolism of the soy isoflavone glycitein.
2007-07
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006-11
Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity.
2006-08-28
Prostatic fluid concentrations of isoflavonoids in soy consumers are sufficient to inhibit growth of benign and malignant prostatic epithelial cells in vitro.
2006-04-01
Isoflavones modulate the glucuronidation of estradiol in human liver microsomes.
2005-12
Identifying 6,7,4'-trihydroxyisoflavone as a potent tyrosinase inhibitor.
2005-10
DPPH radical-scavenging compounds from dou-chi, a soybean fermented food.
2005-05
Novel tempeh (fermented soyabean) isoflavones inhibit in vivo angiogenesis in the chicken chorioallantoic membrane assay.
2005-03
[Mechanism of mono-hydroxylation of daidzein in human liver microsomes].
2004-11
Isolation of 8-hydroxyglycitein and 6-hydroxydaidzein from soybean miso.
2004-06
Genistein and daidzein induce cell proliferation and their metabolites cause oxidative DNA damage in relation to isoflavone-induced cancer of estrogen-sensitive organs.
2004-03-09
Evidence for the involvement of human liver microsomes CYP1A2 in the mono-hydroxylation of daidzein.
2003-08
Antimutagenic activity of 8-hydroxyisoflavones and 6-hydroxydaidzein from soybean miso.
2003-04
Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies.
2002-12
Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo.
2001-06
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.
2001-03
Flavonoid 6-hydroxylase from soybean (Glycine max L.), a novel plant P-450 monooxygenase.
2001-01-19
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 21:26:58 GMT 2025
Edited
by admin
on Mon Mar 31 21:26:58 GMT 2025
Record UNII
PLM2K574GE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
4',6,7-TRIHYDROXYISOFLAVONE
Common Name English
6,7,4'-TRIHYDROXYISOFLAVONE
Preferred Name English
4H-1-BENZOPYRAN-4-ONE, 6,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-
Systematic Name English
6-HYDROXYDAIDZEIN
Common Name English
DESMETHYLGLYCITEIN
Common Name English
ISOFLAVONE, 4',6,7-TRIHYDROXY-
Common Name English
Code System Code Type Description
CAS
17817-31-1
Created by admin on Mon Mar 31 21:26:58 GMT 2025 , Edited by admin on Mon Mar 31 21:26:58 GMT 2025
PRIMARY
EPA CompTox
DTXSID8022452
Created by admin on Mon Mar 31 21:26:58 GMT 2025 , Edited by admin on Mon Mar 31 21:26:58 GMT 2025
PRIMARY
PUBCHEM
5284649
Created by admin on Mon Mar 31 21:26:58 GMT 2025 , Edited by admin on Mon Mar 31 21:26:58 GMT 2025
PRIMARY
FDA UNII
PLM2K574GE
Created by admin on Mon Mar 31 21:26:58 GMT 2025 , Edited by admin on Mon Mar 31 21:26:58 GMT 2025
PRIMARY
CHEBI
74957
Created by admin on Mon Mar 31 21:26:58 GMT 2025 , Edited by admin on Mon Mar 31 21:26:58 GMT 2025
PRIMARY