Details
| Stereochemistry | UNKNOWN |
| Molecular Formula | C12H17NO3 |
| Molecular Weight | 223.2683 |
| Optical Activity | ( - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC1=CC=C(NC(=O)CC(C)O)C=C1
InChI
InChIKey=LIAWQASKBFCRNR-UHFFFAOYSA-N
InChI=1S/C12H17NO3/c1-3-16-11-6-4-10(5-7-11)13-12(15)8-9(2)14/h4-7,9,14H,3,8H2,1-2H3,(H,13,15)
| Molecular Formula | C12H17NO3 |
| Molecular Weight | 223.2683 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
DescriptionCurator's Comment: http://www.genome.jp/dbget-bin/www_bget?D01116
http://www.drugfuture.com/chemdata/bucetin.html
Curator's Comment: http://www.genome.jp/dbget-bin/www_bget?D01116
http://www.drugfuture.com/chemdata/bucetin.html
Bucetin [(3-hydroxy-p-butyrophenetidide) CAS: 1083-57-4) is a homologue to phenacetin and is used instead of phenacetin as an analgesic drug because of its lower toxicity than that of phenacetin, despite having equivalent analgesic activity when used at an appropriate dose. Dysplastic lesions of the proximal tubules were frequently seen in the males given bucetin in a dose-related fashion.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice. | 1987-11 |
|
| Drug absorption, metabolism, and excretion. 3. Synthesis of the metabolites of bucetin (beta-hydroxybutyro-p-phenetidide). | 1968-11 |
|
| Drug absorption, metabolism, and excretion. II. Metabolism of bucetin (beta-hydroxybutyro-p-phenetidide) in rabbits. | 1968-09 |
|
| Studies on absorption and excretion of drug. 8. The release rate in vivo of antipyretic and analgesic drugs from commercial sugar coated tablets. | 1967-07 |
|
| [Study on Butylon, a new combined analgesic, with special reference to the analgesic potentiation between o-ethoxybenzamide and 3-hydroxy-p-burtyrophenetidide (Bucetin)]. | 1966-05-20 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:13:18 GMT 2025
by
admin
on
Mon Mar 31 23:13:18 GMT 2025
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| Record UNII |
PLF54F8S2F
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Common Name | English | ||
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Preferred Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
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156674-10-1
Created by
admin on Mon Mar 31 23:13:18 GMT 2025 , Edited by admin on Mon Mar 31 23:13:18 GMT 2025
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PLF54F8S2F
Created by
admin on Mon Mar 31 23:13:18 GMT 2025 , Edited by admin on Mon Mar 31 23:13:18 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
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RACEMATE -> ENANTIOMER |
