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Details

Stereochemistry ACHIRAL
Molecular Formula C12H4Cl6
Molecular Weight 360.878
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,2',3,3',4,4'-HEXACHLOROBIPHENYL

SMILES

ClC1=C(Cl)C(Cl)=C(C=C1)C2=C(Cl)C(Cl)=C(Cl)C=C2

InChI

InChIKey=BTAGRXWGMYTPBY-UHFFFAOYSA-N
InChI=1S/C12H4Cl6/c13-7-3-1-5(9(15)11(7)17)6-2-4-8(14)12(18)10(6)16/h1-4H

HIDE SMILES / InChI

Molecular Formula C12H4Cl6
Molecular Weight 360.878
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease.
2014-09-15
Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture.
2014-08-01
Non-dioxin-like PCBs inhibit [(3)H]WIN-35,428 binding to the dopamine transporter: a structure-activity relationship study.
2013-12
Effects of oil pollution and persistent organic pollutants (POPs) on glycerophospholipids in liver and brain of male Atlantic cod (Gadus morhua).
2013-02
Effects of developmental exposure to polychlorinated biphenyls and/or polybrominated diphenyl ethers on cochlear function.
2011-11
In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans.
2011-05
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.
2011-04
Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells.
2009-12-10
An exploratory study of diabetes in a First Nation community with respect to serum concentrations of p,p'-DDE and PCBs and fish consumption.
2009-12
Polychlorinated biphenyls modulated tumorigenesis in Sprague Dawley rats: correlation with mixed function oxidase activities and superoxide (O2* ) formation potentials and implied mode of action.
2007-08
Polychlorinated biphenyl-induced neurotoxicity in organotypic cocultures of developing rat ventral mesencephalon and striatum.
2007-05
Polychlorinated biphenyl-induced reduction of dopamine transporter expression as a precursor to Parkinson's disease-associated dopamine toxicity.
2006-08
In vitro profiling of the endocrine-disrupting potency of brominated flame retardants.
2006-07
Combined and individual administration of diethyl phthalate and polychlorinated biphenyls and its toxicity in female Wistar rats.
2006-01
Acute exposure to aroclor 1016 or 1260 differentially affects dopamine transporter and vesicular monoamine transporter 2 levels.
2004-03-14
Vesicular catecholamine release from rat PC12 cells on acute and subchronic exposure to polychlorinated biphenyls.
2002-09-15
Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding.
2002-03-15
Inhibition of gap junctional intercellular communication in normal human breast epithelial cells after treatment with pesticides, PCBs, and PBBs, alone or in mixtures.
1996-02
Short-term study of the combined effects of mirex, photomirex, and kepone with halogenated biphenyls in rats.
1980-03
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:06:28 GMT 2025
Edited
by admin
on Mon Mar 31 22:06:28 GMT 2025
Record UNII
PJ11O9J71Y
Record Status Validated (UNII)
Record Version
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Name Type Language
2,2',3,3',4,4'-HEXACHLOROBIPHENYL
Systematic Name English
PCB 128
Preferred Name English
Code System Code Type Description
CAS
38380-07-3
Created by admin on Mon Mar 31 22:06:28 GMT 2025 , Edited by admin on Mon Mar 31 22:06:28 GMT 2025
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EPA CompTox
DTXSID50858932
Created by admin on Mon Mar 31 22:06:28 GMT 2025 , Edited by admin on Mon Mar 31 22:06:28 GMT 2025
PRIMARY
FDA UNII
PJ11O9J71Y
Created by admin on Mon Mar 31 22:06:28 GMT 2025 , Edited by admin on Mon Mar 31 22:06:28 GMT 2025
PRIMARY
PUBCHEM
38018
Created by admin on Mon Mar 31 22:06:28 GMT 2025 , Edited by admin on Mon Mar 31 22:06:28 GMT 2025
PRIMARY