U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:58:39 GMT 2023
Edited
by admin
on Sat Dec 16 14:58:39 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
PIV978KC1N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM CHANNEL PROTEIN TYPE 1 SUBUNIT ALPHA
Common Name English
SCN1A Protein
Common Name English
NAC1
Common Name English
SODIUM CHANNEL PROTEIN BRAIN I SUBUNIT ALPHA
Common Name English
SCN1
Common Name English
VOLTAGE-GATED SODIUM CHANNEL SUBUNIT ALPHA NAV1.1
Common Name English
NAV 1.1
Common Name English
SODIUM CHANNEL PROTEIN TYPE I SUBUNIT ALPHA
Common Name English
Code System Code Type Description
UNIPROT
P35498
Created by admin on Sat Dec 16 14:58:40 GMT 2023 , Edited by admin on Sat Dec 16 14:58:40 GMT 2023
PRIMARY
FDA UNII
PIV978KC1N
Created by admin on Sat Dec 16 14:58:40 GMT 2023 , Edited by admin on Sat Dec 16 14:58:40 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_211
N 1_284
N 1_295
N 1_301
N 1_306
N 1_338
N 1_1378
N 1_1392
N 1_1403
Related Record Type Details
INHIBITOR -> TARGET
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Shifts hNav1.1 opening to more depolarized voltages without further alterations in the gating properties of hNav1.1, hNav1.2, hNav1.3, and hNav1.6;
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Binds to inactivated state and prevents activation
INHIBITOR -> TARGET
INHIBITOR -> TARGET
EC50
INDUCER OF EXPRESSION->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL