NKG2-A/NKG2-B TYPE II INTEGRAL MEMBRANE PROTEIN

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:24:15 GMT 2025` Edited by `admin` on `Tue Apr 01 21:24:15 GMT 2025`
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	PI49HI2X2K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NKG2-A/NKG2-B TYPE II INTEGRAL MEMBRANE PROTEIN

Common Name

English

CD159A

Preferred Name

English

NKG2A

Code

English

KLRC1

Code

English

CD159 ANTIGEN-LIKE FAMILY MEMBER A

Common Name

English

NKG2-A/B-ACTIVATING NK RECEPTOR

Common Name

English

NK CELL RECEPTOR A

Common Name

English

Code System Code Type Description

UNIPROT

P26715

Created by admin on Tue Apr 01 21:24:15 GMT 2025 , Edited by admin on Tue Apr 01 21:24:15 GMT 2025

PRIMARY

FDA UNII

PI49HI2X2K

Created by admin on Tue Apr 01 21:24:15 GMT 2025 , Edited by admin on Tue Apr 01 21:24:15 GMT 2025

PRIMARY

From	To
1_119	1_130
1_147	1_229
1_208	1_221

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_102
N	1_103
N	1_151
N	1_180

Related Record Type Details


					C41SJ1JYR1

Zimistobart

INHIBITOR -> TARGET

Comments:

Inhibits the interaction between HLA-E and the NKG2A receptor. Inhibition of the NKG2A-HLA-E interaction blocks the HLA-E-mediated inhibitory NKG2A signal and is hypothesized to restore both T and NK cell antitumor responses

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL