Details
Stereochemistry | ACHIRAL |
Molecular Formula | C3HCl2N3O3 |
Molecular Weight | 197.964 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
ClN1C(=O)NC(=O)N(Cl)C1=O
InChI
InChIKey=CEJLBZWIKQJOAT-UHFFFAOYSA-N
InChI=1S/C3HCl2N3O3/c4-7-1(9)6-2(10)8(5)3(7)11/h(H,6,9,10)
Molecular Formula | C3HCl2N3O3 |
Molecular Weight | 197.964 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
DescriptionCurator's Comment: description was created based on several sources, including:
http://www.preciseformulation.com/nadcc-tablets-general-applications.html | http://akvopedia.org/wiki/Chlorine_(NaDCC) | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b345ae6a-0b36-45c7-b31e-2a15508a2ef5 | https://www.ncbi.nlm.nih.gov/pubmed/20064989
Curator's Comment: description was created based on several sources, including:
http://www.preciseformulation.com/nadcc-tablets-general-applications.html | http://akvopedia.org/wiki/Chlorine_(NaDCC) | https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b345ae6a-0b36-45c7-b31e-2a15508a2ef5 | https://www.ncbi.nlm.nih.gov/pubmed/20064989
Troclosene is chlorinated hydroxytriazine and it is used as a source of free available chlorine, in the form of hypochlorous acid, for the disinfection of water. It kills bacteria, bacterial spores, cysts, algae, fungi, protozoa and virus and are especially lethal to Entamoeba histolytica. Troclosene kills mastitis-causing organisms. It is now widely available for household water treatment. It does not prevent diarrhea but improved water quality.
Approval Year
PubMed
Title | Date | PubMed |
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The efficacy of chemical agents in cleaning and disinfection programs. | 2001 |
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Life threatening airway obstruction in a newborn following ingestion of sterilising tablet. | 2001 Nov |
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Germicidal activities of representatives of five different teat dip classes against three bovine mycoplasma species using a modified excised teat model. | 2002 Aug |
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Reduction of mastitis caused by experimental challenge with Staphylococcus aureus and Streptococcus agalactiae by use of a quaternary ammonium and halogen-mixture teat dip. | 2002 Jan |
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[Bioactive effectiveness of selected disinfective agents on Gram-negative bacilli isolated from hospital environment]. | 2004 |
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The effect of a range of disinfectants on the dimensional accuracy of some impression materials. | 2004 Dec |
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The effect of sterilization methods on the light transmission characteristics and structure of light-curing tips. | 2004 Sep |
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Chlorine covers on living bacteria: the initial step in antimicrobial action of active chlorine compounds. | 2005 Apr |
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[Study on the resistance of Escherichia coli O157:H7 to disinfectants in relationship with its plasmid pO157 and chromosome DNA]. | 2005 Nov |
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[Comparison on resistance of bacteriophages to sodium dichloroisocyanurate in laboratory]. | 2006 Jan |
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Sodium dichloroisocyanurate (NaDCC) tablets as an alternative to sodium hypochlorite for the routine treatment of drinking water at the household level. | 2006 Mar |
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Whole-genome analysis of the SHORT-ROOT developmental pathway in Arabidopsis. | 2006 May |
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Analytical method for the quantitative determination of cyanuric acid as the degradation product of sodium dichloroisocyanurate in urine by liquid chromatography mass spectrometry. | 2007 Jun 15 |
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Virucidal agents in the eve of manorapid synergy. | 2007 Sep 13 |
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UV-visible marker confirms that environmental persistence of Clostridium difficile spores in toilets of patients with C. difficile-associated diarrhea is associated with lack of compliance with cleaning protocol.e. | 2008 May 12 |
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Disinfection of irreversible hydrocolloid impression material with chlorinated compounds. | 2009 Jun |
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[Specific antisepsis and environmental disinfection in preventing "Clostridium difficile associated diarrhea"]. | 2009 Nov-Dec |
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Disinfection efficacy of sodium dichloroisocyanurate (NADCC) against common food-borne intestinal protozoa. | 2010 Apr |
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Improvements to water purification and sanitation infrastructure may reduce the diarrheal burden in a marginalized and flood prone population in remote Nicaragua. | 2010 Dec 8 |
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Consumer exposure to biocides--identification of relevant sources and evaluation of possible health effects. | 2010 Feb 3 |
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Disinfection by-product formation and mitigation strategies in point-of-use chlorination with sodium dichloroisocyanurate in Tanzania. | 2010 Jul |
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Jasmonic acid and ethylene modulate local responses to wounding and simulated herbivory in Nicotiana attenuata leaves. | 2010 Jun |
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Root canal irrigants. | 2010 Oct |
|
Field assessment of a novel household-based water filtration device: a randomised, placebo-controlled trial in the Democratic Republic of Congo. | 2010 Sep 10 |
Patents
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1971634
Viral suspensions were prepared containing 10(4)-10(5) syncitial forming units ml-1 in 0.9% saline or 0.9% saline containing 10% v/v plasma to simulate clean and dirty conditions. A syncitial inhibition assay on C8166 lymphoblastoid line was used to determine viral titre. Results indicate that satisfactory disinfection (3-4 log reduction in 2 min) can be achieved using Troclosene and NaOCl at concentrations of 50 ppm and 2500 ppm available chlorine (AvCl2) for clean and soiled conditions respectively. For treatment of blood spillages, the addition of Troclosene and NaOCl solutions (10,000 ppm) to equal volumes of contaminated blood (giving a final AvCl2 concentration of 5000 ppm of blood) was sufficient to produce total kill within 2 min.
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:50:10 GMT 2023
by
admin
on
Fri Dec 15 16:50:10 GMT 2023
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Record UNII |
PHR838Y52L
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Record Status |
Validated (UNII)
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Record Version |
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EPA PESTICIDE CODE |
81401
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16726
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2782-57-2
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5897
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DTXSID8024993
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C011765
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1537576
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Dichloroisocyanuric acid
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PHR838Y52L
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220-487-5
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SALT/SOLVATE -> PARENT |
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ACTIVE MOIETY |