MOBENZOXAMINE

Details

Stereochemistry	RACEMIC
Molecular Formula	C30H35FN2O3
Molecular Weight	490.6089
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(C=C1)C(OCCN2CCN(CCCC(=O)C3=CC=C(F)C=C3)CC2)C4=CC=CC=C4

InChI

InChIKey=DFNYDADZMXPPLY-UHFFFAOYSA-N

InChI=1S/C30H35FN2O3/c1-35-28-15-11-26(12-16-28)30(25-6-3-2-4-7-25)36-23-22-33-20-18-32(19-21-33)17-5-8-29(34)24-9-13-27(31)14-10-24/h2-4,6-7,9-16,30H,5,8,17-23H2,1H3

HIDE SMILES / InChI

Molecular Formula	C30H35FN2O3
Molecular Weight	490.6089
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3243512

Mobenzoxamine is gastro-intestinal function modulator, that enhanced gastric emptying. In preclinical models clathrate compound of mobenzoxamine with beta-cyclodextrin showed a clear amelioration of the delayed gastric emptying induced by Barium chloride. On isolated guinea pig ileum, Mobenzoxamine inhibited contractions induced by various agonists equally to or more potently than trimebutine or papaverine.

Originator

Approval Year

PubMed

Title	Date	PubMed
[Pharmacological studies on the clathrate compound of mobenzoxamine with beta-cyclodextrin. (I). Effects on the digestive system].	1988-11	3243512

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:49:02 GMT 2025` Edited by `admin` on `Mon Mar 31 18:49:02 GMT 2025`
Record UNII	PH0033A74X
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MOBENZOXAMINE

Official Name

English

4'-FLUORO-4-(4-(2-((P-METHOXY-.ALPHA.-PHENYLBENZYL)OXY)ETHYL)-1-PIPERAZINYL)BUTYROPHENONE

Preferred Name

English

mobenzoxamine [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29698