RETINOID X RECEPTOR ALPHA

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 03:18:55 GMT 2025` Edited by `admin` on `Wed Apr 02 03:18:55 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	PG6GA793XH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NR2B1

Preferred Name

English

RETINOID X RECEPTOR ALPHA

Common Name

English

RETINOIC ACID RECEPTOR RXR-ALPHA

Common Name

English

RXRA

Common Name

English

NUCLEAR RECEPTOR SUBFAMILY 2 GROUP B MEMBER 1

Common Name

English

RXR.ALPHA.

Common Name

English

Code System Code Type Description

UNIPROT

P19793

Created by admin on Wed Apr 02 03:18:55 GMT 2025 , Edited by admin on Wed Apr 02 03:18:55 GMT 2025

PRIMARY

FDA UNII

PG6GA793XH

Created by admin on Wed Apr 02 03:18:55 GMT 2025 , Edited by admin on Wed Apr 02 03:18:55 GMT 2025

PRIMARY

Linkage Type	Residue Index
COORDINATION COMPOUND	1_135	1_138	1_152	1_155
COORDINATION COMPOUND	1_171	1_177	1_187	1_190

Related Record Type Details


					LCH760E9T7

ACITRETIN

INHIBITOR -> TARGET

Amount:


					0462Z4S4OZ

OBETICHOLIC ACID

INHIBITOR -> TARGET

Interaction Type:

INHIBITOR

Qualification:

EC50

Amount:


					877M97Z38Y

VTP-194204

AGONIST -> TARGET

Amount:


					1UA8E65KDZ

Alitretinoin

AGONIST -> TARGET

Amount:


					4S7931G4PP

K-80003

INHIBITOR -> TARGET


					A61RXM4375

BEXAROTENE

AGONIST -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_56] [1_70] [1_260]		DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[1_135] [1_138] [1_152] [1_155]	SITE_SPECIFIC	C4-TYPE ZINC FINGER	C56TF4V7OP
AMINO ACID SUBSTITUTION	[1_82]		THREONINE PHOSPHATE	3L4WX7B1EI
AMINO_ACID_SUBSTITUTION	[1_171] [1_177] [1_187] [1_190]	SITE_SPECIFIC	C4-TYPE ZINC FINGER	C56TF4V7OP
AMINO ACID SUBSTITUTION	[1_21] [1_27] [1_259]		DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL