U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sun Jun 27 00:29:21 UTC 2021
Edited
by admin
on Sun Jun 27 00:29:21 UTC 2021
Protein Sub Type
Sequence Type COMPLETE
Record UNII
PG6GA793XH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
RETINOID X RECEPTOR ALPHA
Common Name English
NR2B1
Common Name English
RETINOIC ACID RECEPTOR RXR-ALPHA
Common Name English
RXRA
Common Name English
NUCLEAR RECEPTOR SUBFAMILY 2 GROUP B MEMBER 1
Common Name English
RXR.ALPHA.
Common Name English
Code System Code Type Description
UNIPROT
P19793
Created by admin on Sun Jun 27 00:29:21 UTC 2021 , Edited by admin on Sun Jun 27 00:29:21 UTC 2021
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
Inhibits the interaction of the N-terminally truncated RXRα (tRXRα) with the p85α subunit of PI3K, leading to suppression of AKT activation and induction of apoptosis.
ALLOSTERIC INHIBITOR
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR
EC50
AGONIST -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL
Molecular Formula CHEMICAL