Lunlekitug

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:00:17 GMT 2025` Edited by `admin` on `Wed Apr 02 11:00:17 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	PD7XVG7CKK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Lunlekitug

Official Name

English

XB20-12

Preferred Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens human interleukin-1? (Hematopoietin-1)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV1-69*01 (80.4%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.

Common Name

English

lunlekitug [INN]

Common Name

English

LUNLEKITUG [USAN]

Common Name

English

XB2012

Code

English

Immunoglobulin G1, anti-(human interleukin 1?) (human monoclonal XB20-12 ?1-chain), disulfide with human monoclonal XB20-12 ?-chain, dimer

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C206937

Created by admin on Wed Apr 02 11:00:17 GMT 2025 , Edited by admin on Wed Apr 02 11:00:17 GMT 2025

PRIMARY

CAS

2640257-30-1

Created by admin on Wed Apr 02 11:00:17 GMT 2025 , Edited by admin on Wed Apr 02 11:00:17 GMT 2025

PRIMARY

FDA UNII

PD7XVG7CKK

Created by admin on Wed Apr 02 11:00:17 GMT 2025 , Edited by admin on Wed Apr 02 11:00:17 GMT 2025

PRIMARY

INN

13159

Created by admin on Wed Apr 02 11:00:17 GMT 2025 , Edited by admin on Wed Apr 02 11:00:17 GMT 2025

PRIMARY

USAN

LM-216

Created by admin on Wed Apr 02 11:00:17 GMT 2025 , Edited by admin on Wed Apr 02 11:00:17 GMT 2025

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SMS_ID

300000054731

Created by admin on Wed Apr 02 11:00:17 GMT 2025 , Edited by admin on Wed Apr 02 11:00:17 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_145	2_201
2_221	4_220
2_262	2_322
1_145	1_201
2_368	2_426
3_23	3_94
3_140	3_200
4_23	4_94
4_140	4_200
1_221	3_220
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					8666ZWZ3E1

INTERLEUKIN-1.ALPHA. (RECOMBINANT, NON-GLYCOSYLATED)

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					PD7XVG7CKK

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL				Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL