BUTACAINE SULFATE

US Previously Marketed

First marketed in 1920

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C18H30N2O2.H2O4S
Molecular Weight	710.964
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OS(O)(=O)=O.CCCCN(CCCC)CCCOC(=O)C1=CC=C(N)C=C1.CCCCN(CCCC)CCCOC(=O)C2=CC=C(N)C=C2

InChI

InChIKey=VWZAGCZUPZKTET-UHFFFAOYSA-N

InChI=1S/2C18H30N2O2.H2O4S/c2*1-3-5-12-20(13-6-4-2)14-7-15-22-18(21)16-8-10-17(19)11-9-16;1-5(2,3)4/h2*8-11H,3-7,12-15,19H2,1-2H3;(H2,1,2,3,4)

HIDE SMILES / InChI

Molecular Formula	C18H30N2O2
Molecular Weight	306.443
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/12174527

Butacaine is a local anesthetic. It should not be used with people who have a history of allergies due to the possibility of anaphylactic shock.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

Sourcing

Vendor/Aggregator	ID	URL
001 Chemical	DY525482	https://www.001chemical.com/chem/149-16-6
AA Blocks	AA001L9K	https://www.aablocks.com/goods/Goods/detail?id=AA001L9K
AK Scientific, Inc. (AKSCI)	2290AH	http://www.aksci.com/item_detail.php?cat=2290AH
AbMole Bioscience	M2480	http://www.abmole.com/products/butacaine.html
Aurora Fine Chemicals LLC	A17.878.231	http://online.aurorafinechemicals.com/info?ID=A17.878.231
BLD Pharm	BD119003	http://www.bldpharm.com/products/149-16-6.html
BioSynth	J-008557	https://www.biosynth.com/en/products/all-products/products/J-008557.html
BioSynth	J-008559	https://www.biosynth.com/en/products/all-products/products/J-008559.html
CSNpharm	CSN10514	https://www.csnpharm.com/products/butacaine.html
Chem Scene	CS-4504	http://www.chemscene.com/149-16-6.html
ChemMol	49416082	http://www.chemmol.com/chemmol/49416082.html
Chemspace	CSSB00020618021	https://chem-space.com/CSSB00020618021
Lab Network	LN00194991	https://labnetwork.com/frontend-app/p/#!/moleculedetails/LN00194991
MedChem Express	HY-B1007	https://www.medchemexpress.com/Butacaine.html
Molcore	MC525482	https://www.molcore.com/product/149-16-6
MuseChem	I001834	https://www.musechem.com/product/I001834.html
mcule	MCULE-4554935124	https://mcule.com/MCULE-4554935124/

PubMed

Title	Date	PubMed
Keratitis from misuse of corneal anesthetics.	1968 Aug 22	4232838
Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria.	2001 Apr 15	11295535
Managing patients with local anesthetic complications using alternative methods.	2002 May-Jun	12174527
PAMPA - excipient classification gradient map.	2006 Nov	17053953
Solubility-excipient classification gradient maps.	2007 Mar	17245653

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

The specific activities of two transferases, aspartate-amino-transferase and creatine phosphokinase, are increased by 10(-5) mol/l butacaine

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:00:27 GMT 2023` Edited by `admin` on `Fri Dec 15 15:00:27 GMT 2023`
Record UNII	PAU39W3CVB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BUTACAINE SULFATE

Common Name

English

BUTACAINE SULFATE [MART.]

Common Name

English

BUTACAINE SULPHATE

Common Name

English

BUTACAINE SULFATE [MI]

Common Name

English

3-(DIBUTYLAMINO)-1-PROPANOL P-AMINOBENZOATE (ESTER) SULFATE (2:1)

Common Name

English

1-PROPANOL, 3-(DIBUTYLAMINO)-, 4-AMINOBENZOATE (ESTER), SULPHATE (SALT) (2:1)

Common Name

English

Butacaine sulfate [WHO-DD]

Common Name

English

BUTACAINE SULFATE [GREEN BOOK]

Common Name

English

1-PROPANOL, 3-(DIBUTYLAMINO)-, 4-AMINOBENZOATE (ESTER), SULFATE (SALT) (2:1)

Common Name

English

3-(DIBUTYLAMINO)-1-PROPANOL P-AMINOBENZOATE (ESTER) SULPHATE (2:1)

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C245