Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H4N2.BrH |
| Molecular Weight | 148.989 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Br.N1C=CN=C1
InChI
InChIKey=VWUCIBOKNZGWLX-UHFFFAOYSA-N
InChI=1S/C3H4N2.BrH/c1-2-5-3-4-1;/h1-3H,(H,4,5);1H
| Molecular Formula | BrH |
| Molecular Weight | 80.912 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C3H4N2 |
| Molecular Weight | 68.0773 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Imidazole salicylate (also known as ITF-182), a nonsteroidal anti-inflammatory drug (NSAID) that inhibits Tromboxane A2 synthesis, without interfering with cyclo-oxygenase pathway and possesses the limited inhibitory effects on prostaglandin synthesis. Imidazole salicylate can be used for the treatment of osteoarthrosis and musculoskeletal trauma. In addition, it can be given to patients with decompensated cirrhosis without risk of inhibiting kidney prostaglandin synthesis. Imidazole salicylate was characterized by good gastric tolerability and could be assigned for treatment of rheumatic diseases in the elderly. The drug also can be safely used in aspirin-sensitive patients.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Tolerability of imidazole salycilate in aspirin-sensitive patients. | 1995-09-01 |
|
| Effects of imidazole-salicylate on renal function and the diuretic action of furosemide in cirrhotic patients with ascites. | 1993-09 |
|
| Blood binding of selezen (imidazole salicylate) in man. | 1991-06 |
|
| Double-blind randomized clinical trial on imidazole salicylate vs ibuprofen in osteoarthritis. | 1991-05 |
|
| Imidazole salicylate versus piroxicam in the treatment of arthrosis in elderly patients. A double-blind clinical and endoscopic trial. | 1990-09 |
|
| Imidazole salicylate in the treatment of osteoarthrosis and musculoskeletal trauma: a postmarketing survey. | 1988 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 23:30:02 GMT 2025
by
admin
on
Mon Mar 31 23:30:02 GMT 2025
|
| Record UNII |
P8OZC543Y6
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID901335873
Created by
admin on Mon Mar 31 23:30:02 GMT 2025 , Edited by admin on Mon Mar 31 23:30:02 GMT 2025
|
PRIMARY | |||
|
12203052
Created by
admin on Mon Mar 31 23:30:02 GMT 2025 , Edited by admin on Mon Mar 31 23:30:02 GMT 2025
|
PRIMARY | |||
|
101023-55-6
Created by
admin on Mon Mar 31 23:30:02 GMT 2025 , Edited by admin on Mon Mar 31 23:30:02 GMT 2025
|
PRIMARY | |||
|
P8OZC543Y6
Created by
admin on Mon Mar 31 23:30:02 GMT 2025 , Edited by admin on Mon Mar 31 23:30:02 GMT 2025
|
PRIMARY |