Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C15H19N6O6.K |
| Molecular Weight | 418.4463 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[K+].C[C@@H](O)[C@@H]1[C@H]2OC(=C(N2C1=O)C([O-])=O)C(C)(C)CNC(=O)CN3C=NN=N3
InChI
InChIKey=AFIOJKXUVZFDHY-HGSORSNPSA-M
InChI=1S/C15H20N6O6.K/c1-7(22)9-12(24)21-10(14(25)26)11(27-13(9)21)15(2,3)5-16-8(23)4-20-6-17-18-19-20;/h6-7,9,13,22H,4-5H2,1-3H3,(H,16,23)(H,25,26);/q;+1/p-1/t7-,9+,13-;/m1./s1
| Molecular Formula | K |
| Molecular Weight | 39.0983 |
| Charge | 1 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C15H19N6O6 |
| Molecular Weight | 379.348 |
| Charge | -1 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 3 / 3 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
596 ng/mL |
100 mg single, oral dose: 100 mg route of administration: Oral experiment type: SINGLE co-administered: |
AM-152 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
701.9 ng/mL |
100 mg 1 times / day multiple, oral dose: 100 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
AM-152 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
3380.8 ng × h/mL |
100 mg single, oral dose: 100 mg route of administration: Oral experiment type: SINGLE co-administered: |
AM-152 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
6048.3 ng × h/mL |
100 mg 1 times / day multiple, oral dose: 100 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
AM-152 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
22.9 h |
100 mg single, oral dose: 100 mg route of administration: Oral experiment type: SINGLE co-administered: |
AM-152 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
Funbound
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
0.2% EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/35090952/# |
AM-152 plasma | Homo sapiens |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:59:00 GMT 2025
by
admin
on
Mon Mar 31 19:59:00 GMT 2025
|
| Record UNII |
P7GO2JAC07
|
| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID10217900
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23674543
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675839-33-5
Created by
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P7GO2JAC07
Created by
admin on Mon Mar 31 19:59:00 GMT 2025 , Edited by admin on Mon Mar 31 19:59:00 GMT 2025
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PARENT -> SALT/SOLVATE |
