BATELAPINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H20N6
Molecular Weight	296.3702
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BATELAPINE

Structure Search

SMILES

CN1CCN(CC1)C2=NC3=CC=CC=C3CC4=NC(C)=NN24

InChI

InChIKey=PUHMYHQVPODHCZ-UHFFFAOYSA-N

InChI=1S/C16H20N6/c1-12-17-15-11-13-5-3-4-6-14(13)18-16(22(15)19-12)21-9-7-20(2)8-10-21/h3-6H,7-11H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C16H20N6
Molecular Weight	296.3702
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7619892 | https://adisinsight.springer.com/drugs/800007160

Batelapine (or CGS 13429), an antipsychotic drug, that was undergoing preclinical development, but the further studied were discontinued

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
High-performance liquid chromatographic method for a clozapine analogue, CGS 13429, and its N-oxide and desmethyl metabolites.	1989 Sep 29	2573611
Determination of in vivo hepatic extraction ratio from in vitro metabolism by rat hepatocytes.	1991 Sep-Oct	1686248

Patents

Patents

Sample Use Guides

In Vivo Use Guide

single oral ascending doses ranging from 0.1 to 10 mg in healthy male voluntee

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:23:08 GMT 2023` Edited by `admin` on `Sat Dec 16 16:23:08 GMT 2023`
Record UNII	P71TE299SG
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BATELAPINE

Official Name

English

batelapine [INN]

Common Name

English

2-METHYL-5-(4-METHYL-1-PIPERAZINYL)-11H-S-TRIAZOLO(1,5-C)(1,3)BENZODIAZEPINE

Systematic Name

English

11H-(1,2,4)TRIAZOLO(1,5-C)(1,3)BENZODIAZEPINE, 2-METHYL-5-(4-METHYL-1-PIPERAZINYL)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

Code System Code Type Description

CAS

95634-82-5

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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EPA CompTox

DTXSID50241906

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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EVMPD

SUB06110MIG

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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WIKIPEDIA

Batelapine

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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NCI_THESAURUS

C76436

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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PUBCHEM

60717

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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FDA UNII

P71TE299SG

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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ChEMBL

CHEMBL2110765

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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SMS_ID

100000081333

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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INN

6721

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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MESH

C061853

Created by admin on Sat Dec 16 16:23:08 GMT 2023 , Edited by admin on Sat Dec 16 16:23:08 GMT 2023

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Related Record Type Details


					66K342SF4G

BATELAPINE MALEATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					P71TE299SG

ACTIVE MOIETY