Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12HF23O2 |
| Molecular Weight | 614.0984 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI
InChIKey=CXGONMQFMIYUJR-UHFFFAOYSA-N
InChI=1S/C12HF23O2/c13-2(14,1(36)37)3(15,16)4(17,18)5(19,20)6(21,22)7(23,24)8(25,26)9(27,28)10(29,30)11(31,32)12(33,34)35/h(H,36,37)
| Molecular Formula | C12HF23O2 |
| Molecular Weight | 614.0984 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver. | 2016-06 |
|
| Structure-activity relations in binding of perfluoroalkyl compounds to human thyroid hormone T3 receptor. | 2015-02 |
|
| Structure-dependent binding and activation of perfluorinated compounds on human peroxisome proliferator-activated receptor γ. | 2014-09-15 |
|
| Evaluation of perfluoroalkyl acid activity using primary mouse and human hepatocytes. | 2013-06-07 |
|
| In vitro toxicological characterization of perfluorinated carboxylic acids with different carbon chain lengths. | 2013-04-12 |
|
| Phosphoproteome analysis reveals an important role for glycogen synthase kinase-3 in perfluorododecanoic acid-induced rat liver toxicity. | 2013-03-27 |
|
| Activation of mouse and human peroxisome proliferator-activated receptor-alpha (PPARα) by perfluoroalkyl acids (PFAAs): further investigation of C4-C12 compounds. | 2012-07 |
|
| Transcriptional effects of perfluorinated compounds in rat hepatoma cells. | 2012-01 |
|
| Estrogen-like activity of perfluoroalkyl acids in vivo and interaction with human and rainbow trout estrogen receptors in vitro. | 2011-03 |
|
| Concentrations, distribution, and persistence of perfluoroalkylates in sludge-applied soils near Decatur, Alabama, USA. | 2010-11-15 |
|
| Metabolic changes reveal the development of schistosomiasis in mice. | 2010-08-31 |
|
| Perfluorinated compounds in urban river sediments from Guangzhou and Shanghai of China. | 2010-06 |
|
| Perfluorinated compounds, polychlorinated biphenyls, and organochlorine pesticide contamination in composite food samples from Dallas, Texas, USA. | 2010-06 |
|
| Perfluorododecanoic acid-induced steroidogenic inhibition is associated with steroidogenic acute regulatory protein and reactive oxygen species in cAMP-stimulated Leydig cells. | 2010-04 |
|
| Chitosan-coated octadecyl-functionalized magnetite nanoparticles: preparation and application in extraction of trace pollutants from environmental water samples. | 2010-03-15 |
|
| Binding of perfluorocarboxylates to serum albumin: a comparison of analytical methods. | 2010-02-01 |
|
| Proteomic analysis for testis of rats chronically exposed to perfluorododecanoic acid. | 2010-02-01 |
|
| Occurrence of perfluoroalkyl carboxylates and sulfonates in drinking water utilities and related waters from the United States. | 2009-12-15 |
|
| Determination of ten perfluorinated compounds in bluegill sunfish (Lepomis macrochirus) fillets. | 2009-11 |
|
| Combined effects of polyfluorinated and perfluorinated compounds on primary cultured hepatocytes from rare minnow (Gobiocypris rarus) using toxicogenomic analysis. | 2009-10-19 |
|
| Perfluorinated compounds in sediments from the Daliao River system of northeast China. | 2009-10 |
|
| Effects of 18 perfluoroalkyl compounds on mRNA expression in chicken embryo hepatocyte cultures. | 2009-10 |
|
| Miscibility and phase behavior of DPPG and perfluorocarboxylic acids at the air-water interface. | 2009-10 |
|
| Miscibility behavior of two-component monolayers at the air-water interface: perfluorocarboxylic acids and DMPE. | 2009-09-01 |
|
| Chronic exposure to perfluorododecanoic acid disrupts testicular steroidogenesis and the expression of related genes in male rats. | 2009-08-10 |
|
| Do perfluoroalkyl compounds impair human semen quality? | 2009-06 |
|
| The effect of perfluorododecanonic acid on endocrine status, sex hormones and expression of steroidogenic genes in pubertal female rats. | 2009-06 |
|
| Temporal trends of polyfluoroalkyl compounds in harbor seals (Phoca vitulina) from the German Bight, 1999-2008. | 2009-06 |
|
| Systems biological responses to chronic perfluorododecanoic acid exposure by integrated metabonomic and transcriptomic studies. | 2009-06 |
|
| Fluorescence study on site-specific binding of perfluoroalkyl acids to human serum albumin. | 2009-03 |
|
| Evaluation of wastewater and street runoff as sources of perfluorinated surfactants (PFSs). | 2009-01 |
|
| Perfluorocarboxylic acids induce cytochrome P450 enzymes in mouse liver through activation of PPAR-alpha and CAR transcription factors. | 2008-11 |
|
| Time trends and transplacental transfer of perfluorinated compounds in melon-headed whales stranded along the Japanese coast in 1982, 2001/2002, and 2006. | 2008-10-01 |
|
| Induction of time-dependent oxidative stress and related transcriptional effects of perfluorododecanoic acid in zebrafish liver. | 2008-09-29 |
|
| Skipjack tuna as a bioindicator of contamination by perfluorinated compounds in the oceans. | 2008-09-15 |
|
| Occurrence and sources of perfluorinated surfactants in rivers in Japan. | 2008-09-01 |
|
| Toxic effect of serial perfluorosulfonic and perfluorocarboxylic acids on the membrane system of a freshwater alga measured by flow cytometry. | 2008-07 |
|
| Fluorotelomer alcohols induce hepatic vitellogenin through activation of the estrogen receptor in male medaka (Oryzias latipes). | 2008-05 |
|
| Lipid homeostasis and oxidative stress in the liver of male rats exposed to perfluorododecanoic acid. | 2008-02-15 |
|
| Purification and thermal analysis of perfluoro-n-alkanoic acids. | 2008-01-15 |
|
| Emissions of perfluorinated alkylated substances (PFAS) from point sources--identification of relevant branches. | 2008 |
|
| [A method of perfluorinated organic compounds in drinking water determinated by HPLC-MS/MS]. | 2007-11 |
|
| Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and comparisons with NHANES 1999-2000. | 2007-11 |
|
| Perfluorinated compounds in the Pearl River and Yangtze River of China. | 2007-08 |
|
| Alterations in gene expression and testosterone synthesis in the testes of male rats exposed to perfluorododecanoic acid. | 2007-07 |
|
| Occurrence of perfluorooctane sulfonate and other perfluorinated alkylated substances in harbor porpoises from the Black Sea. | 2007-01-01 |
|
| Rapid response of Arctic ringed seals to changes in perfluoroalkyl production. | 2007-01-01 |
|
| Perfluorooctanesulfonate and related fluorochemicals in albatrosses, elephant seals, penguins, and polar skuas from the Southern Ocean. | 2006-12-15 |
|
| Perfluorooctanesulfonate and related fluorochemicals in human blood samples from China. | 2006-02-01 |
|
| Alkaline digestion and solid phase extraction method for perfluorinated compounds in mussels and oysters from South China and Japan. | 2006-02 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:27:26 GMT 2025
by
admin
on
Mon Mar 31 22:27:26 GMT 2025
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| Record UNII |
P6G1J7NM2D
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID8031861
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206-203-2
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P6G1J7NM2D
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90633
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307-55-1
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67545
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