U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:19:24 GMT 2023
Edited
by admin
on Sat Dec 16 12:19:24 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
P6ECO9K4CI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
POLYCOMB PROTEIN EED
Common Name English
WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLASMIC TAILS 1
Common Name English
WAIT-1
Common Name English
EED
Common Name English
HEED
Common Name English
Code System Code Type Description
UNIPROT
O75530
Created by admin on Sat Dec 16 12:19:24 GMT 2023 , Edited by admin on Sat Dec 16 12:19:24 GMT 2023
PRIMARY
FDA UNII
P6ECO9K4CI
Created by admin on Sat Dec 16 12:19:24 GMT 2023 , Edited by admin on Sat Dec 16 12:19:24 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
FTX-6058 acts via inhibition of the polycomb repressive complex 2 (PRC2) through binding to the embryonic ectoderm development (EED) subunit. A 2-3 fold increase in fetal hemoglobulin sysnthesiswhen treated.
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL