POLYCOMB PROTEIN EED

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:59:01 GMT 2025` Edited by `admin` on `Tue Apr 01 18:59:01 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	P6ECO9K4CI
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

POLYCOMB PROTEIN EED

Common Name

English

EED

Preferred Name

English

WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLASMIC TAILS 1

Common Name

English

WAIT-1

Common Name

English

HEED

Common Name

English

Embryonic ectoderm development protein

Common Name

English

Code System Code Type Description

UNIPROT

O75530

Created by admin on Tue Apr 01 18:59:01 GMT 2025 , Edited by admin on Tue Apr 01 18:59:01 GMT 2025

PRIMARY

FDA UNII

P6ECO9K4CI

Created by admin on Tue Apr 01 18:59:01 GMT 2025 , Edited by admin on Tue Apr 01 18:59:01 GMT 2025

PRIMARY

Related Record Type Details


					7HU6337315

ASTEMIZOLE

INHIBITOR -> TARGET


					BC2SSV7WMT

Pociredir

INHIBITOR -> TARGET

Comments:

FTX-6058 acts via inhibition of the polycomb repressive complex 2 (PRC2) through binding to the embryonic ectoderm development (EED) subunit. A 2-3 fold increase in fetal hemoglobulin sysnthesiswhen treated.

Amount:


					L247UMG5ML

EEDi-5273

INHIBITOR -> TARGET

Interaction Type:

PRECLINICAL

Qualification:

IC50

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL