Stereochemistry | ACHIRAL |
Molecular Formula | C13H10O4 |
Molecular Weight | 230.2161 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2C(=O)C=C(C)OC2=CC3=C1C=CO3
InChI
InChIKey=NZVQLVGOZRELTG-UHFFFAOYSA-N
InChI=1S/C13H10O4/c1-7-5-9(14)12-11(17-7)6-10-8(3-4-16-10)13(12)15-2/h3-6H,1-2H3
Molecular Formula | C13H10O4 |
Molecular Weight | 230.2161 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Visnagin is furanochromone and one of the main compounds of Ammi visnaga L. (syn. Khella) that can be frequently found in ethnomedical formulations in Asia and the Middle East. Visnagin possess analgesic properties due to its calcium channel blocking properties and act in an anti-inflammatory manner by inhibiting AP-1 and NF-κB signaling.
Originator
Approval Year
Sample Use Guides
Neonatal rat cardiomyocytes were used for activity evaluation. Neonatal rat cardiomyocytes and HL1 cells were stained with fluorescent Annexin V (Roche) and were live imaged after being treated with doxorubicin (1-50mkM), visnagin and diphenylurea for the indicated amounts of time. Apoptosis indices were quantified as percentage of AnnexinV positive cells.