U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Wed Apr 02 19:56:28 GMT 2025
Edited
by admin
on Wed Apr 02 19:56:28 GMT 2025
Protein Type VACCINE ANTIGEN
Protein Sub Type HAPTEN CONJUGATE
Sequence Origin BACTERIAL
Sequence Type COMPLETE
Record UNII
P5Y8UP8ERW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
3?-aminomethylnicotine conjugated to the r-Exoprotein A (rEPA) of Pseudomonas aeruginosa
Common Name English
3'-aminomethyl-Nic r-EPA Conjugate
Preferred Name English
NicVAX antigen
Common Name English
3?-AmNic-rEPA
Common Name English
Code System Code Type Description
FDA UNII
P5Y8UP8ERW
Created by admin on Wed Apr 02 19:56:28 GMT 2025 , Edited by admin on Wed Apr 02 19:56:28 GMT 2025
PRIMARY
Related Record Type Details
TARGET->VACCINE ANTIGEN
Related Record Type Details
ACTIVE MOIETY
The nicotine vaccine, NicVAX, does not appear to improve the chances of stopping smoking when given in addition to varenicline and behavioural support.

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO_ACID_SUBSTITUTION K Amount: N6-Lysyl-succinyl-trans-3?-aminomethylnicotine 5Y8U7X2UKP
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL