THREO-MEFLOQUINE, (-)-

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C17H16F6N2O
Molecular Weight	378.3122
Optical Activity	( - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(CCCCN1)[C@H](O)C2=C3C=CC=C(C3=NC(=C2)C(F)(F)F)C(F)(F)F

InChI

InChIKey=XEEQGYMUWCZPDN-IUODEOHRSA-N

InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H16F6N2O
Molecular Weight	378.3122
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:06:32 GMT 2023` Edited by `admin` on `Sat Dec 16 10:06:32 GMT 2023`
Record UNII	P4QYS7TV8C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

THREO-MEFLOQUINE, (-)-

Common Name

English

RAC-(R)-(2,8-BIS(TRIFLUOROMETHYL)QUINOLIN-4-YL)((2R)-PIPERIDIN-2-YL)METHANOL [WHO-IP]

Common Name

English

MEFLOQUINE HYDROCHLORIDE IMPURITY A [WHO-IP]

Common Name

English

THREO-MEFLOQUINE [WHO-IP]

Common Name

English

4-QUINOLINEMETHANOL, .ALPHA.-(2R)-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-, (.ALPHA.R)-

Systematic Name

English

(.ALPHA.R)-.ALPHA.-(2R)-2-PIPERIDINYL-2,8-BIS(TRIFLUOROMETHYL)-4-QUINOLINEMETHANOL

Systematic Name

English

(-)-THREO-MEFLOQUINE

Common Name

English

THREO-MEFLOQUINE

Common Name

English

Code System Code Type Description

FDA UNII

P4QYS7TV8C

Created by admin on Sat Dec 16 10:06:32 GMT 2023 , Edited by admin on Sat Dec 16 10:06:32 GMT 2023

PRIMARY

CAS

148690-80-6

Created by admin on Sat Dec 16 10:06:32 GMT 2023 , Edited by admin on Sat Dec 16 10:06:32 GMT 2023

PRIMARY

PUBCHEM

3000506

Created by admin on Sat Dec 16 10:06:32 GMT 2023 , Edited by admin on Sat Dec 16 10:06:32 GMT 2023

PRIMARY

Related Record Type Details


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					5Y9L3636O3

MEFLOQUINE HYDROCHLORIDE

PARENT -> IMPURITY

Comments:

In the chromatogram obtained with solution (1) the following impurities, if present, are eluted at the following relative retention with reference to mefloquine (retention time about 3.9 minutes): impurity A about 0.9. In the chromatogram obtained with solution (1):the area of any peak corresponding to impurity A is not greater than the area of the principal peak in the chromatogram obtained with solution (2) (0.2%).