| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H18N2O2 |
| Molecular Weight | 318.3691 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN(CC)C1=CC2=C(C=C1)N=C3C(O2)=CC(=O)C4=CC=CC=C34
InChI
InChIKey=VOFUROIFQGPCGE-UHFFFAOYSA-N
InChI=1S/C20H18N2O2/c1-3-22(4-2)13-9-10-16-18(11-13)24-19-12-17(23)14-7-5-6-8-15(14)20(19)21-16/h5-12H,3-4H2,1-2H3
| Molecular Formula | C20H18N2O2 |
| Molecular Weight | 318.3691 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Nile red (9-diethylamino-5H-benzo[alpha]phenoxazine-5-one) is an excellent vital stain for the detection of intracellular lipid droplets by fluorescence microscopy and flow cytofluorometry. It has environment-sensitive fluorescence. Nile red is intensely fluorescent in a lipid-rich environment while it has minimal fluorescence in aqueous media. Better selectivity for cytoplasmic lipid droplets can be obtained when the cells are viewed with yellow-gold fluorescence (450-500 nm excitation; >528 nm emission) rather than red fluorescence (515-560 nm excitation; >590 nm emission). Nile red is strongly fluorescent, but only in a hydrophobic environment.
CNS Activity
Originator
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
PubMed
Patents
Sample Use Guides
Mice were used to quantify brain uptake of fluorescently-labeled nanoparticles. Nile red-loaded nanoparticles were resuspended in PBS and administered at 200 mg/kg via the tail vein.
Route of Administration:
Intravenous