Timcevibart

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 20:18:28 UTC 2023` Edited by `admin` on `Sat Dec 16 20:18:28 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	P45RTW33K4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Timcevibart

Official Name

English

immunoglobulin G1-kappa, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody

Common Name

English

Immunoglobulin G1 [232-proline,233-valine,234-alanine,263-glycine,325-glutamine,328-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein S1 receptor-binding domain) (human monoclonal COR-101 γ1-chain), disulfide with human m

Common Name

English

timcevibart [INN]

Common Name

English

gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-66*01 (96.9%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v50-79 CH2 delE1.4, P1.3, V1.2, A1.A, G27, Q

Common Name

English

Code System Code Type Description

FDA UNII

P45RTW33K4

Created by admin on Sat Dec 16 20:18:28 UTC 2023 , Edited by admin on Sat Dec 16 20:18:28 UTC 2023

PRIMARY

CAS

2857862-27-0

Created by admin on Sat Dec 16 20:18:28 UTC 2023 , Edited by admin on Sat Dec 16 20:18:28 UTC 2023

PRIMARY

INN

12929

Created by admin on Sat Dec 16 20:18:28 UTC 2023 , Edited by admin on Sat Dec 16 20:18:28 UTC 2023

PRIMARY

From	To
1_22	1_95
2_22	2_95
2_143	2_199
2_219	4_215
2_259	2_319
1_143	1_199
2_365	2_423
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195
1_219	3_215
1_225	2_225
1_228	2_228
1_259	1_319
1_365	1_423

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_295
N	2_295

Related Record Type Details


					B6L4N5Z4GH

SARS-COV2

TARGET ORGANISM->INHIBITOR

Amount:

Related Record Type Details


					P45RTW33K4

Timcevibart

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL