HYDRON III

OC1=C2N=CC=CC2=C(C=C1)N=O

InChIKey=RZWRYPGAUIOOMK-UHFFFAOYSA-N

InChI=1S/C9H6N2O2/c12-8-4-3-7(11-13)6-2-1-5-10-9(6)8/h1-5,12H

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Histone deacetylase 20 Target ID: CHEMBL2093865 Sources: https://www.ncbi.nlm.nih.gov/pubmed/15450938 \| https://www.ncbi.nlm.nih.gov/pubmed/16497787	Inhibitor 8504

PubMed

Title	Date	PubMed
Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells.	2006-05	16497787
Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model.	2004-11-01	15450938

Substance Class	Chemical Created by `admin` on `Tue Apr 01 22:20:40 GMT 2025` Edited by `admin` on `Tue Apr 01 22:20:40 GMT 2025`
Record UNII	P302KW5VDN
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

NSC-3852

Preferred Name

English

HYDRON III

Common Name

English

8-HYDROXY-5-NITROSOQUINOLINE

Systematic Name

English

8-QUINOLINOL, 5-NITROSO-

Systematic Name

English

5-NITROSOOXINE

Systematic Name

English

5-NITROSO-8-HYDROXYQUINOLINE

Systematic Name

English

5-NITROSO-8-QUINOLINOL

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

222-650-6