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Details

Stereochemistry ACHIRAL
Molecular Formula C3H2O2
Molecular Weight 70.0468
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PROPIOLIC ACID

SMILES

OC(=O)C#C

InChI

InChIKey=UORVCLMRJXCDCP-UHFFFAOYSA-N
InChI=1S/C3H2O2/c1-2-3(4)5/h1H,(H,4,5)

HIDE SMILES / InChI

Molecular Formula C3H2O2
Molecular Weight 70.0468
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis of symmetrical and unsymmetrical diarylalkynes from propiolic acid using palladium-catalyzed decarboxylative coupling.
2010-09-17
Regiodivergent ligand-controlled rhodium-catalyzed [(2+2)+2] carbocyclization reactions with alkyl substituted methyl propiolates.
2010-08-02
Temporal effects on spectroscopic line shapes, resolution, and sensitivity of the broad-band sum frequency generation.
2010-06-21
Cu-catalyzed oxidative amidation of propiolic acids under air via decarboxylative coupling.
2010-05-07
Click chemistry aided synthesis of 1,4-substituted 1,2,3-triazole based N-Fmoc protected epsilon-amino acids: isolation, characterization and synthesis of novel triazole based unnatural amino acids.
2010-04
PPh3-catalyzed reactions of alkyl propiolates with N-tosylimines: a facile synthesis of alkyl 2-[aryl(tosylimino)methyl]acrylate and an insight into the reaction mechanism.
2010-02-08
One-pot synthesis of 2-pyridones via chemo- and regioselective tandem Blaise reaction of nitriles with propiolates.
2009-10-02
Structural analysis of glycosphingolipid analogues obtained by the saccharide primer method using CE-ESI-MS.
2009-10
Highly regioselective Au(I)-catalyzed hydroamination of ynamides and propiolic acid derivatives with anilines.
2009-09-17
Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors.
2009-09-10
Highly enantioselective catalytic alkyl propiolate addition to aliphatic aldehydes.
2009-06-04
N-Benzyl-2-propynamide.
2009-04-25
Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy.
2009-04-22
Kinetic glutathione chemoassay to quantify thiol reactivity of organic electrophiles--application to alpha,beta-unsaturated ketones, acrylates, and propiolates.
2009-04
Direct measurement of charge transport through helical poly(ethyl propiolate) nanorods wired into gaps in single walled carbon nanotubes.
2009-03-11
Acetylides from alkyl propiolates as building blocks for C3 homologation.
2009
Si(111) surface modified with alpha,beta-unsaturated carboxyl groups studied by MIR-FTIR.
2008-10-07
Ring expansion of lactones and lactams via propiolate 1-carbon intercalation.
2008-09-18
Thiol detection, derivatization and tagging at micromole to nanomole levels using propiolates.
2008-06
Catalytic addition of alkyne C-H, amine N-H, and phosphine P-H bonds to carbodiimides: an efficient route to propiolamidines, guanidines, and phosphaguanidines.
2008-05-21
Three-component coupling reaction and cyclization of N-tosylimines and TMS-substituted propiolate mediated by DABCO.
2008-03-07
One-pot synthesis of diarylalkynes using palladium-catalyzed sonogashira reaction and decarboxylative coupling of sp carbon and sp2 carbon.
2008-03-06
Synthesis and characterization of polyacetylene with side-chain thiophene functionality.
2008-03
Functional group and substructure searching as a tool in metabolomics.
2008-02-06
Reagentless functionalization of gold nanoparticles via a 3 + 2 Huisgen cycloaddition.
2008-02-01
Methyl 2-(1,3-dioxoisoindolin-2-yl)acrylate.
2007-12-18
Matrix isolation and ab initio study of the HXeCCH...CO2 complex.
2007-10-21
[Development of a new method for consecutive activation of conjugated alkynes based on intramolecular silyl migration].
2007-08
Increases in microbial nitrogen production and efficiency in vitro with three inhibitors of ruminal methanogenesis.
2007-04
Synthesis of modified nucleosides for incorporation of formyletheno and carboxyetheno adducts of adenine nucleosides into oligonucleotides.
2007
UV photolysis products of propiolic acid in noble-gas solids.
2006-10-12
Reaction of thioketones with propiolic acids.
2006-07-21
Chemo-differentiating MCRs based on alpha-ketoesters and terminal alkynoates. A homoaldol-based ABB' system.
2006-07-05
Novel potent and selective alphavbeta3/alphavbeta5 integrin dual antagonists with reduced binding affinity for human serum albumin.
2006-07
Effects of butyrate precursors on electron relocation when methanogenesis is inhibited in ruminal mixed cultures.
2006-06
Trisoxazoline/Cu(II)-promoted Kinugasa reaction. Enantioselective synthesis of beta-lactams.
2006-04-28
Synthesis of substituted chromenes through the DABCO-catalyzed reaction of but-3-yn-2-one and methyl propiolate with salicyl N-tosylimines (DABCO = 1,4-diazabicyclo[2.2.2]octane).
2006-04-12
Monitoring Lactobacillus plantarum in grass silages with the aid of 16S rDNA-based quantitative real-time PCR assays.
2006-01
A new protocol for the consecutive alpha- and beta-activation of propiolates towards electrophiles, involving conjugate addition of tertiary amines and intramolecular silyl migration.
2005-09-05
Inactivation of malonate semialdehyde decarboxylase by 3-halopropiolates: evidence for hydratase activity.
2005-07-05
A practical catalytic method for preparing highly substituted cyclobutanes and cyclobutenes.
2005-03-23
A modular, one-pot, four-component synthesis of polysubstituted 1,3-oxazolidines.
2005-02-04
Reactions of 4-oxalocrotonate tautomerase and YwhB with 3-halopropiolates: analysis and implications.
2004-01-27
Effects of several inhibitors on pure cultures of ruminal methanogens.
2004
Use of some novel alternative electron sinks to inhibit ruminal methanogenesis.
2003-09-06
High-throughput synthesis and optimization of thrombin inhibitors via urazole alpha-addition and Michael addition.
2003-04-17
In situ proton NMR analysis of alpha-alkynoate biotransformations. From 'invisible' substrates to detectable metabolites.
2003-04
A novel modified baylis-hillman reaction of propiolate.
2003-01-22
Synthesis of seven-membered lactones via nickel- and zinc-catalyzed highly regio- and stereoselective cyclization of 2-iodobenzyl alcohols with propiolates.
2002-05-22
Regiochemistry in 1,3-dipolar cycloadditions of the azomethine ylide formed from diethyl aminomalonate and paraformaldehyde.
2002-01-11
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:13:22 GMT 2025
Edited
by admin
on Mon Mar 31 21:13:22 GMT 2025
Record UNII
P2QW39G9LZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-16152
Preferred Name English
PROPIOLIC ACID
MI  
Systematic Name English
2-PROPYNOIC ACID
Systematic Name English
PROPIOLIC ACID [MI]
Common Name English
2-PROPYNE-1-CARBOXYLIC ACID
Systematic Name English
ACETYLENECARBOXYLIC ACID
Systematic Name English
PROPARGYLIC ACID
Common Name English
ACETYLENEMONOCARBOXYLIC ACID
Systematic Name English
Code System Code Type Description
CAS
471-25-0
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
WIKIPEDIA
PROPIOLIC ACID
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
FDA UNII
P2QW39G9LZ
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
ECHA (EC/EINECS)
207-437-8
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
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HSDB
7857
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
MERCK INDEX
m9205
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY Merck Index
PUBCHEM
10110
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
EPA CompTox
DTXSID6060050
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
NSC
16152
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY
CHEBI
33199
Created by admin on Mon Mar 31 21:13:22 GMT 2025 , Edited by admin on Mon Mar 31 21:13:22 GMT 2025
PRIMARY