CINFENINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H27NO
Molecular Weight	357.488
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CINFENINE

Structure Search

SMILES

CN(CCOC(C1=CC=CC=C1)C2=CC=CC=C2)C\C=C\C3=CC=CC=C3

InChI

InChIKey=QTKQVDXGCWKEHE-SDNWHVSQSA-N

InChI=1S/C25H27NO/c1-26(19-11-14-22-12-5-2-6-13-22)20-21-27-25(23-15-7-3-8-16-23)24-17-9-4-10-18-24/h2-18,25H,19-21H2,1H3/b14-11+

HIDE SMILES / InChI

Molecular Formula	C25H27NO
Molecular Weight	357.488
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Description
Sources: https://apps.who.int/iris/bitstream/handle/10665/68742/WHO_EDM_QSM_2004.5.pdf?sequence=1 | DE1936206

Cinfenine is diphenylmethoxyethylamine derivative that acts as antidepressant in some animal models.

Originator

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 09:45:30 GMT 2025` Edited by `admin` on `Wed Apr 02 09:45:30 GMT 2025`
Record UNII	P26FL0O04P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

cinfenine [INN]

Preferred Name

English

CINFENINE

Official Name

English

(E)-N-(2-(DIPHENYLMETHOXY)ETHYL)-N-METHYLCINNAMYLAMINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

Code System Code Type Description

EVMPD

SUB06294MIG

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

NCI_THESAURUS

C78009

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

EPA CompTox

DTXSID101023894

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

SMS_ID

100000081044

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

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ChEMBL

CHEMBL2104102

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

PUBCHEM

6443800

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

CAS

54141-87-6

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

FDA UNII

P26FL0O04P

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

INN

3229

Created by admin on Wed Apr 02 09:45:30 GMT 2025 , Edited by admin on Wed Apr 02 09:45:30 GMT 2025

PRIMARY

Related Record Type Details


					P26FL0O04P

CINFENINE

ACTIVE MOIETY