METACLAZEPAM HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H18BrClN2O.ClH
Molecular Weight	430.166
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.COCC1CN=C(C2=C(Cl)C=CC=C2)C3=C(C=CC(Br)=C3)N1C

InChI

InChIKey=IDCVMXYQJUFZJD-UHFFFAOYSA-N

InChI=1S/C18H18BrClN2O.ClH/c1-22-13(11-23-2)10-21-18(14-5-3-4-6-16(14)20)15-9-12(19)7-8-17(15)22;/h3-9,13H,10-11H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	C18H18BrClN2O
Molecular Weight	393.705
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2868732 | https://www.ncbi.nlm.nih.gov/pubmed/2568645

Metaclazepam is a benzodiazepine derivative. It exerts anxiolytic properties.

CNS Activity

Originator

Approval Year

PubMed

Title	Date	PubMed
Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization.	2004 Aug	15329838

Sample Use Guides

In Vivo Use Guide

patients with anxiety syndrome were treated either with placebo, or with 15 mg or with 30 mg metaclazepam/day for two weeks

Route of Administration: Oral

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:24:11 GMT 2023` Edited by `admin` on `Fri Dec 15 16:24:11 GMT 2023`
Record UNII	P21PFK193T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METACLAZEPAM HYDROCHLORIDE

Common Name

English

7-BROMO-5-(2-CHLOROPHENYL)-2,3-DIHYDRO-2-(METHOXYMETHYL)-1-METHYL-1H-1,4-BENZODIAZEPINE HYDROCHLORIDE

Systematic Name

English

METACLAZEPAM HYDROCHLORIDE [MI]

Common Name

English

Metaclazepam hydrochloride [WHO-DD]

Common Name

English

METACLAZEPAM HCL

Common Name

English

METACLAZEPAM HYDROCHLORIDE [MART.]

Common Name

English

7-BROMO-5-(O-CHLOROPHENYL)-2,3-DIHYDRO-2-(METHOXYMETHYL)-1-METHYL-1H-1,4-BENZODIAZEPINE HYDROCHLORIDE

Common Name

English

BROMETAZEPAM HYDROCHLORIDE

Common Name

English

METUCLAZEPAM HYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1012