U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C34H66O10P.Na
Molecular Weight 688.8454
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM 1,2-DIMYRISTOYL-SN-GLYCERO-3-(PHOSPHO-S-(1-GLYCEROL))

SMILES

[Na+].CCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OC[C@@H](O)CO)OC(=O)CCCCCCCCCCCCC

InChI

InChIKey=QLNOOKSBAYIHQI-XJEPUKKESA-M
InChI=1S/C34H67O10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-33(37)41-29-32(30-43-45(39,40)42-28-31(36)27-35)44-34(38)26-24-22-20-18-16-14-12-10-8-6-4-2;/h31-32,35-36H,3-30H2,1-2H3,(H,39,40);/q;+1/p-1/t31-,32+;/m0./s1

HIDE SMILES / InChI

Molecular Formula C34H66O10P
Molecular Weight 665.8556
Charge -1
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

1,2-DIMYRISTOYL-SN-GLYCERO-3-(PHOSPHO-S-(1-GLYCEROL)), SODIUM SALT is a prototype for the preparation of liposomes with negatively charged hydrophilic head groups. It can be used in the generation of different types of artificial membranes.

Approval Year

PubMed

PubMed

TitleDatePubMed
Thermal transitions in the bilayer assembly of dimyristoylphosphatidylglycerol sodium salt dispersion in water: a new phase transition through an intermediate state.
2000 Dec 11
A Fourier transform infrared spectroscopic study of the interaction of alkaline earth cations with the negatively charged phospholipid 1, 2-dimyristoyl-sn-glycero-3-phosphoglycerol.
2000 Jun 1
Enhanced bactericidal potency of nanoliposomes by modification of the fusion activity between liposomes and bacterium.
2013
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:38:03 GMT 2023
Edited
by admin
on Fri Dec 15 15:38:03 GMT 2023
Record UNII
P17P4C999T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM 1,2-DIMYRISTOYL-SN-GLYCERO-3-(PHOSPHO-S-(1-GLYCEROL))
Common Name English
1,2-DIMYRISTOYL-SN-GLYCERO-3-(PHOSPHO-S-(1-GLYCEROL)), SODIUM SALT
Common Name English
TETRADECANOIC ACID, 1-((((2,3-DIHYDROXYPROPOXY)HYDROXYPHOSPHINYL)OXY)METHYL)-1,2-ETHANEDIYL ESTER, MONOSODIUM SALT, (R-(R*,S*))-
Systematic Name English
Code System Code Type Description
PUBCHEM
72941659
Created by admin on Fri Dec 15 15:38:03 GMT 2023 , Edited by admin on Fri Dec 15 15:38:03 GMT 2023
PRIMARY
FDA UNII
P17P4C999T
Created by admin on Fri Dec 15 15:38:03 GMT 2023 , Edited by admin on Fri Dec 15 15:38:03 GMT 2023
PRIMARY
CAS
116870-30-5
Created by admin on Fri Dec 15 15:38:03 GMT 2023 , Edited by admin on Fri Dec 15 15:38:03 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE