U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 10:21:31 GMT 2023
Edited
by admin
on Sat Dec 16 10:21:31 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Type COMPLETE
Record UNII
P0GVQ9A4S5
Record Status Validated (UNII)
Record Version
  • Download
Related Record Type
Name Type Language
DOSTARLIMAB
USAN   INN  
Official Name English
TSR-042
Code English
GSK-4057190
Code English
dostarlimab [INN]
Common Name English
GSK4057190
Code English
IMMUNOGLOBULIN G4, ANTI-(PROGRAMMED CELL DEATH PROTEIN 1 (PDCD1)) (HUMANIZED CLONE ABT1 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED CLONE ABT1 .KAPPA.-CHAIN, DIMER
Systematic Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HUMAN PROGRAMMED CELL DEATH PROPTEIN 1 (PROTEIN PD-1, CD279 ANTIGEN))HUMANIZED MONOCLONAL ANTIBODY: .GAMMA.4 HEAVY CHAIN (1-440) (HUMANIZED VH (HOMO SAPIENS IGHV3-23*01 (92%) (IGHD)-IGHJ6*01 (93%)) (8.8.6) (1-113) -HOMO SAP
Systematic Name English
Dostarlimab [WHO-DD]
Common Name English
DOSTARLIMAB [USAN]
Common Name English
WBP-285
Code English
Code System Code Type Description
RXCUI
2539967
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
NCI_THESAURUS
C126799
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
USAN
EF-55
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
FDA UNII
P0GVQ9A4S5
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
INN
10787
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
WIKIPEDIA
Dostarlimab
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
SMS_ID
100000181573
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
DAILYMED
P0GVQ9A4S5
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
DRUG BANK
DB15627
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
CAS
2022215-59-2
Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023
PRIMARY
From To
1_22 1_96
1_130 3_214
1_143 1_199
1_222 2_222
1_225 2_225
1_257 1_317
1_363 1_421
2_22 2_96
2_130 4_214
2_143 2_199
2_257 2_317
2_363 2_421
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_293
N 2_293
Related Record Type Details
TARGET -> INHIBITOR
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL