DOSTARLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 10:21:31 GMT 2023` Edited by `admin` on `Sat Dec 16 10:21:31 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Type	COMPLETE
Record UNII	P0GVQ9A4S5
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

DOSTARLIMAB

Official Name

English

TSR-042

Code

English

GSK-4057190

Code

English

dostarlimab [INN]

Common Name

English

GSK4057190

Code

English

IMMUNOGLOBULIN G4, ANTI-(PROGRAMMED CELL DEATH PROTEIN 1 (PDCD1)) (HUMANIZED CLONE ABT1 .GAMMA.4-CHAIN), DISULFIDE WITH HUMANIZED CLONE ABT1 .KAPPA.-CHAIN, DIMER

Systematic Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HUMAN PROGRAMMED CELL DEATH PROPTEIN 1 (PROTEIN PD-1, CD279 ANTIGEN))HUMANIZED MONOCLONAL ANTIBODY: .GAMMA.4 HEAVY CHAIN (1-440) (HUMANIZED VH (HOMO SAPIENS IGHV3-23*01 (92%) (IGHD)-IGHJ6*01 (93%)) (8.8.6) (1-113) -HOMO SAP

Systematic Name

English

Dostarlimab [WHO-DD]

Common Name

English

DOSTARLIMAB [USAN]

Common Name

English

WBP-285

Code

English

Code System Code Type Description

RXCUI

2539967

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

NCI_THESAURUS

C126799

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

USAN

EF-55

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

FDA UNII

P0GVQ9A4S5

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

INN

10787

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

WIKIPEDIA

Dostarlimab

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

SMS_ID

100000181573

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

DAILYMED

P0GVQ9A4S5

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

DRUG BANK

DB15627

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

CAS

2022215-59-2

Created by admin on Sat Dec 16 10:21:31 GMT 2023 , Edited by admin on Sat Dec 16 10:21:31 GMT 2023

PRIMARY

From	To
1_22	1_96
1_130	3_214
1_143	1_199
1_222	2_222
1_225	2_225
1_257	1_317
1_363	1_421
2_22	2_96
2_130	4_214
2_143	2_199
2_257	2_317
2_363	2_421
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194

Glycosylation Link Type	Site
N	1_293
N	2_293

Related Record Type Details


					938DNF64FO

PROGRAMMED CELL DEATH PROTEIN 1

TARGET -> INHIBITOR

Amount:

DOSTARLIMAB-GXLY

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					P0GVQ9A4S5

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL