ALMASILATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2Al.Mg.2O4Si.H2O
Molecular Weight	280.4496
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.[Mg++].[Al+3].[Al+3].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-]

InChI

InChIKey=XFKLULFTFNRQOX-UHFFFAOYSA-N

InChI=1S/2Al.Mg.2O4Si.H2O/c;;;2*1-5(2,3)4;/h;;;;;1H2/q2*+3;+2;2*-4;

HIDE SMILES / InChI

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	O4Si
Molecular Weight	92.0831
Charge	-4
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Al
Molecular Weight	26.9815386
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugbank.ca/drugs/DB13595 | https://dtb.bmj.com/content/23/10/39

Almasilate is an antacid compound, consisting of a crystalline aluminum/magnesium silicate polymer. It guffers gastric acid by binding hydrogen ions within the polymer. It has been used in peptic ulcers and dyspepsia and marketed under the tradename Malinal, however, its therapeutic efficacy was lower than that of other approved antacids.

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 05:20:13 GMT 2025` Edited by `admin` on `Wed Apr 02 05:20:13 GMT 2025`
Record UNII	OZQ8O62H53
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

almasilate [INN]

Preferred Name

English

ALMASILATE

Official Name

English

SILICIC ACID (H4SIO4), ALUMINUM MAGNESIUM SALT (2:2:1), HYDRATE

Common Name

English

MALINAL

Brand Name

English

Almasilate [WHO-DD]

Common Name

English

MAGNESIUM ALUMINOSILICATE (MGAL(SUB 2)SI(SUB 2)O(SUB 8)) HYDRATE

Common Name

English

MAGNESIUM ALUMINOSILICATE [JAN]

Common Name

English

MEGALAC

Brand Name

English

ALMASILATE [MART.]

Common Name

English

Classification Tree Code System Code

WHO-ATC

A02AD05