ALDRIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H8Cl6
Molecular Weight	364.91
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12[C@H]3C[C@H](C=C3)[C@@]1([H])[C@@]4(Cl)C(Cl)=C(Cl)[C@]2(Cl)C4(Cl)Cl

InChI

InChIKey=QBYJBZPUGVGKQQ-SJJAEHHWSA-N

InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10+,11-

HIDE SMILES / InChI

Molecular Formula	C12H8Cl6
Molecular Weight	364.91
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver.	1983 Apr	6191977
Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.).	1991 Feb	1904046
Effect of some pesticides/weedicides on cathepsin B activity and lysosomal membrane.	1993 Jun	8406551
Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain.	1997 Jun	9304792
The Drosophila cytochrome P450 gene Cyp6a2: structure, localization, heterologous expression, and induction by phenobarbital.	1997 Nov	9407006
Induction of hepatic cytochrome P-450 by phenobarbital in semi-aquatic frog (Rana pipiens).	1998 Mar 27	9535735
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006 Nov	16497524
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.	2006 Nov 10	16996190
In silico prediction of pregnane X receptor activators by machine learning approaches.	2007 Jan	17003167
Discriminating the molecular basis of hepatotoxicity using the large-scale characteristic molecular signatures of toxicants by expression profiling analysis.	2008 Jul 30	18579281
Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003.	2008 May 15	18343878
Differential effects exerted on human mammary epithelial cells by environmentally relevant organochlorine pesticides either individually or in combination.	2009 Aug 14	19422813
Pesticide use and thyroid disease among women in the Agricultural Health Study.	2010 Feb 15	20061368
Regulation of cytochrome P450 expression in Drosophila: Genomic insights.	2010 Jun 1	20582327
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.	2011 Apr	21295777
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.	2011 Feb 27	21115097
Genetic susceptibility loci, pesticide exposure and prostate cancer risk.	2013	23593118
Risk of total and aggressive prostate cancer and pesticide use in the Agricultural Health Study.	2013 Jan 1	23171882
Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study.	2013 Oct	24064777
Aldrin epoxidation in flathead mullet (Mugil cephalus): possible involvement of CYP1A and CYP3A.	2014 Jun	24756956

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:58:27 GMT 2023` Edited by `admin` on `Fri Dec 15 14:58:27 GMT 2023`
Record UNII	OZE3CLY605
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALDRIN

Common Name

English

ALDRIN [ISO]

Common Name

English

NSC-8937

Code

English

HHDN

Common Name

English

ALDRIN [IARC]

Common Name

English

ALDRIN [HSDB]

Common Name

English

(1R,4S,4AS,5S,8R,8AR)-1,2,3,4,10,10-HEXACHLORO-1,4,4A,5,8,8A-HEXAHYDRO-1,4:5,8-DIMETHANONAPHTHALENE

Common Name

English

ALDRIN [MI]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

45101