ALDRIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H8Cl6
Molecular Weight	364.91
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=C(Cl)[C@]2(Cl)[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3[C@@]1(Cl)C2(Cl)Cl

InChI

InChIKey=QBYJBZPUGVGKQQ-SJJAEHHWSA-N

InChI=1S/C12H8Cl6/c13-8-9(14)11(16)7-5-2-1-4(3-5)6(7)10(8,15)12(11,17)18/h1-2,4-7H,3H2/t4-,5+,6+,7-,10+,11-

HIDE SMILES / InChI

Molecular Formula	C12H8Cl6
Molecular Weight	364.91
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Aldrin epoxidation in flathead mullet (Mugil cephalus): possible involvement of CYP1A and CYP3A.	2014-06	24756956
Hypothyroidism and pesticide use among male private pesticide applicators in the agricultural health study.	2013-10	24064777
Risk of total and aggressive prostate cancer and pesticide use in the Agricultural Health Study.	2013-01-01	23171882
Genetic susceptibility loci, pesticide exposure and prostate cancer risk.	2013	23593118
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines.	2011-04	21295777
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays.	2011-02-27	21115097
Regulation of cytochrome P450 expression in Drosophila: Genomic insights.	2010-06-01	20582327
Pesticide use and thyroid disease among women in the Agricultural Health Study.	2010-02-15	20061368
Differential effects exerted on human mammary epithelial cells by environmentally relevant organochlorine pesticides either individually or in combination.	2009-08-14	19422813
Discriminating the molecular basis of hepatotoxicity using the large-scale characteristic molecular signatures of toxicants by expression profiling analysis.	2008-07-30	18579281
Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003.	2008-05-15	18343878
In silico prediction of pregnane X receptor activators by machine learning approaches.	2007-01	17003167
Modulation of aromatase activity and mRNA by various selected pesticides in the human choriocarcinoma JEG-3 cell line.	2006-11-10	16996190
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Activation of alpha- and beta-estrogen receptors by persistent pesticides in reporter cell lines.	2006-08-15	16626760
Detection of pesticide residues in muscles, liver and fat of 3 species of Labeo found in Kalri and Haleji lakes.	2005-06	16334280
Activation of retinoic acid receptor-dependent transcription by organochlorine pesticides.	2005-01-01	15589975
Drosophila melanogaster CYP6A8, an insect P450 that catalyzes lauric acid (omega-1)-hydroxylation.	2004-12-24	15555597
A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides.	2004-12-15	15548381
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells.	2004-04	15064155
Recombinant human estrogen, androgen and progesterone receptors for detection of potential endocrine disruptors.	2004-02	14579009
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.	2003-10	14565775
Non-Hodgkin's lymphoma and specific pesticide exposures in men: cross-Canada study of pesticides and health.	2001-11	11700263
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens.	2001-03	11258977
Induction of hepatic cytochrome P-450 by phenobarbital in semi-aquatic frog (Rana pipiens).	1998-03-27	9535735
The Drosophila cytochrome P450 gene Cyp6a2: structure, localization, heterologous expression, and induction by phenobarbital.	1997-11	9407006
Cytochrome P450 genes from Helicoverpa armigera: expression in a pyrethroid-susceptible and -resistant strain.	1997-06	9304792
Effect of some pesticides/weedicides on cathepsin B activity and lysosomal membrane.	1993-06	8406551
Gene mapping and cross-resistance in cyclodiene insecticide-resistant Drosophila melanogaster (Mg.).	1991-02	1904046
Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver.	1983-04	6191977

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:33:34 GMT 2025` Edited by `admin` on `Mon Mar 31 17:33:34 GMT 2025`
Record UNII	OZE3CLY605
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-8937

Preferred Name

English

ALDRIN

Common Name

English

ALDRIN [ISO]

Common Name

English

HHDN

Common Name

English

ALDRIN [IARC]

Common Name

English

ALDRIN [HSDB]

Common Name

English

(1R,4S,4AS,5S,8R,8AR)-1,2,3,4,10,10-HEXACHLORO-1,4,4A,5,8,8A-HEXAHYDRO-1,4:5,8-DIMETHANONAPHTHALENE

Common Name

English

ALDRIN [MI]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

45101