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Details

Stereochemistry RACEMIC
Molecular Formula C18H19NOS
Molecular Weight 297.415
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Para-Naphthol duloxetine

SMILES

CNCCC(C1=CC=CS1)C2=C3C=CC=CC3=C(O)C=C2

InChI

InChIKey=OJXMJLCWKLPCHB-UHFFFAOYSA-N
InChI=1S/C18H19NOS/c1-19-11-10-16(18-7-4-12-21-18)14-8-9-17(20)15-6-3-2-5-13(14)15/h2-9,12,16,19-20H,10-11H2,1H3

HIDE SMILES / InChI
Molecular Formula C18H19NOS
Molecular Weight 297.415
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Description

Para-Naphthol Duloxetine is a metabolite of the drug duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) and is used for the treatment depression, anxiety.

Originator

Pharmathen
1
Sources: Evrykleia Karagiannidou, Elli Vastardi Theodoros Panagiotidis, Theodoros Tsatsas, Efstratios Neokosmidis. CHARACTERIZATION OF DULOXETINE HCL API AND ITS PROCESS RELATED IMPURITIES. 2014. IJAPBS.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:14:38 GMT 2025
Edited
by admin
on Mon Mar 31 21:14:38 GMT 2025
Record UNII
OX55AL7074
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DULOXETINE IMPURITY C
USP  
Preferred Name English
Para-Naphthol duloxetine
Common Name English
(±)-PARA-NAPHTHOL DULOXETINE
Common Name English
DULOXETINE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
Common Name English
1-NAPHTHALENOL, 4-(3-(METHYLAMINO)-1-(2-THIENYL)PROPYL)-
Systematic Name English
DULOXETINE IMPURITY C [USP IMPURITY]
Common Name English
4-[(1RS)-3-(methylamino)-1-(thiophen-2-yl)propyl]naphthalen-1-ol
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID801211008
Created by admin on Mon Mar 31 21:14:38 GMT 2025 , Edited by admin on Mon Mar 31 21:14:38 GMT 2025
PRIMARY
PUBCHEM
23641781
Created by admin on Mon Mar 31 21:14:38 GMT 2025 , Edited by admin on Mon Mar 31 21:14:38 GMT 2025
PRIMARY
FDA UNII
OX55AL7074
Created by admin on Mon Mar 31 21:14:38 GMT 2025 , Edited by admin on Mon Mar 31 21:14:38 GMT 2025
PRIMARY
CAS
949095-98-1
Created by admin on Mon Mar 31 21:14:38 GMT 2025 , Edited by admin on Mon Mar 31 21:14:38 GMT 2025
PRIMARY
Related Record Type Details
Structure of Duloxetine hydrochloride
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