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Details

Stereochemistry ACHIRAL
Molecular Formula C7H5NO4S
Molecular Weight 199.184
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2-NITRO-5-THIOBENZOIC ACID

SMILES

OC(=O)C1=CC(S)=CC=C1[N+]([O-])=O

InChI

InChIKey=GANZODCWZFAEGN-UHFFFAOYSA-N
InChI=1S/C7H5NO4S/c9-7(10)5-3-4(13)1-2-6(5)8(11)12/h1-3,13H,(H,9,10)

HIDE SMILES / InChI

Molecular Formula C7H5NO4S
Molecular Weight 199.184
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Acetaminophen induces apoptosis in rat cortical neurons.
2010-12-10
Short-term preservation of porcine oocytes in ambient temperature: novel approaches.
2010-12-07
Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, α synuclein aggregation, oxidative damage and behavioral changes.
2010-11-13
Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice.
2010-10-12
A novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes.
2010-08-19
The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages.
2010-08-15
Association between arsenic exposure and plasma cholinesterase activity: a population based study in Bangladesh.
2010-07-10
Possibilities and pitfalls in quantifying the extent of cysteine sulfenic acid modification of specific proteins within complex biofluids.
2010-07-01
Effect of dietary fats on oxidative-antioxidative status of blood in rats.
2010-07
The application of the yeast N-acetyltransferase MPR1 gene and the proline analogue L-azetidine-2-carboxylic acid as a selectable marker system for plant transformation.
2010-06
Biotransformation of prasugrel, a novel thienopyridine antiplatelet agent, to the pharmacologically active metabolite.
2010-06
Protein antioxidant response to the stress and the relationship between molecular structure and antioxidant function.
2010-01-29
Increase of reactive oxygen species by desferrioxamine during experimental Chagas' disease.
2010
Reduction of ischemic and oxidative damage to the hypothalamus by hyperbaric oxygen in heatstroke mice.
2010
No Modifying Effect of Antioxidant N-Acetyl-L-Cysteine on Fenofibrate-induced Hepatocarcinogenesis in Rats.
2009-12
Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan.
2009-11-05
Synthesis of guanosine and deoxyguanosine phosphoramidites with cross-linkable thioalkyl tethers for direct incorporation into RNA and DNA.
2009-11
Kinetics and mechanisms of the reaction of hypothiocyanous acid with 5-thio-2-nitrobenzoic acid and reduced glutathione.
2009-11
Protective effect of transgenic expression of porcine heat shock protein 70 on hypothalamic ischemic and oxidative damage in a mouse model of heatstroke.
2009-09-03
Stabilization of peptide vesicles by introducing inter-peptide disulfide bonds.
2009-09
Adsorption and inhibition of acetylcholinesterase by different nanoparticles.
2009-09
Phytic Acid Exposure Alters AflatoxinB1-induced Reproductive and Oxidative Toxicity in Albino Rats (Rattus norvegicus).
2009-09
Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance.
2009-07-29
Development of a bioactive paper sensor for detection of neurotoxins using piezoelectric inkjet printing of sol-gel-derived bioinks.
2009-07-01
Effects of N-acetyl-cysteine on endothelial function and inflammation in patients with type 2 diabetes mellitus.
2009-06-30
Alterations in the glutathione metabolism could be implicated in the ischemia-induced small intestinal cell damage in horses.
2009-03-18
Plasma protein thiols, ceruloplasmin, C-reactive protein and red blood cell acetylcholinesterase in patients undergoing intrauterine insemination.
2009-01
Evaluation of cholinesterase activities during in vivo intoxication using an electrochemical sensor strip - correlation with intoxication symptoms.
2009
Ferric reducing antioxidant power and square wave voltammetry for assay of low molecular weight antioxidants in blood plasma: performance and comparison of methods.
2009
The role of the embryo and ethylene in avocado fruit mesocarp discoloration.
2009
Heterologous expression analyses of rice OsCAS in Arabidopsis and in yeast provide evidence for its roles in cyanide detoxification rather than in cysteine synthesis in vivo.
2009
Mycobacterium tuberculosis Rv3802c encodes a phospholipase/thioesterase and is inhibited by the antimycobacterial agent tetrahydrolipstatin.
2009
Determination of thiols and disulfides via HPLC quantification of 5-thio-2-nitrobenzoic acid.
2008-12-15
The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise.
2008-11-07
Measurement of protein sulfenic acid content.
2008-11
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.
2008-09
The effect of aqueous extract of Embelia ribes Burm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia.
2008-08
Identification and antioxidant activity of melanin isolated from Hypoxylon archeri, a companion fungus of Tremella fuciformis.
2008-06
Construction of the active site of glutathione peroxidase on polymer-based nanoparticles.
2008-05
Determination of total and oxidized glutathione in human whole blood with a sequential injection analysis system.
2008-02-15
Oxidation of 5-thio-2-nitrobenzoic acid, by the biologically relevant oxidants peroxynitrite anion, hydrogen peroxide and hypochlorous acid.
2008-02
Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade.
2008-01-02
Leishmanicidal metabolites from Cochliobolus sp., an endophytic fungus isolated from Piptadenia adiantoides (Fabaceae).
2008
Effect of pre-germinated brown rice intake on diabetic neuropathy in streptozotocin-induced diabetic rats.
2007-11-23
Limitation of the Ellman method: cholinesterase activity measurement in the presence of oximes.
2007-11-15
Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase.
2007-08
Relationship between redox activity and chemical speciation of size-fractionated particulate matter.
2007-06-07
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target.
2007-06
Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa.
2007-03-20
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method.
2006
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:21:32 GMT 2025
Edited
by admin
on Mon Mar 31 19:21:32 GMT 2025
Record UNII
OWT399B07G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELLMAN'S ANION FREE ACID
Preferred Name English
2-NITRO-5-THIOBENZOIC ACID
Common Name English
3-CARBOXY-4-NITROBENZENETHIOL
Systematic Name English
BENZOIC ACID, 5-MERCAPTO-2-NITRO-
Systematic Name English
2-NITRO-5-MERCAPTOBENZOIC ACID
Systematic Name English
5-MERCAPTO-2-NITROBENZOIC ACID
Systematic Name English
2-NITRO-5-THIOLBENZOIC ACID
Systematic Name English
Code System Code Type Description
PUBCHEM
123648
Created by admin on Mon Mar 31 19:21:32 GMT 2025 , Edited by admin on Mon Mar 31 19:21:32 GMT 2025
PRIMARY
DRUG BANK
DB02763
Created by admin on Mon Mar 31 19:21:32 GMT 2025 , Edited by admin on Mon Mar 31 19:21:32 GMT 2025
PRIMARY
FDA UNII
OWT399B07G
Created by admin on Mon Mar 31 19:21:32 GMT 2025 , Edited by admin on Mon Mar 31 19:21:32 GMT 2025
PRIMARY
CAS
15139-21-6
Created by admin on Mon Mar 31 19:21:32 GMT 2025 , Edited by admin on Mon Mar 31 19:21:32 GMT 2025
PRIMARY
EPA CompTox
DTXSID80864561
Created by admin on Mon Mar 31 19:21:32 GMT 2025 , Edited by admin on Mon Mar 31 19:21:32 GMT 2025
PRIMARY