U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:31:54 GMT 2023
Edited
by admin
on Sat Dec 16 13:31:54 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
OUP4QB2A3R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FELADILIMAB
INN   USAN  
Official Name English
feladilimab [INN]
Common Name English
FELADILIMAB [USAN]
Common Name English
GSK-609
Code English
GSK-3359609
Code English
ANTI-ICOS AGONIST ANTIBODY GSK3359609
Common Name English
GSK3359609
Code English
IMMUNOGLOBULIN G4 (229-PROLINE,236-GLUTAMIC ACID), ANTI-(HUMAN INDUCIBLE T-CELL CO-STIMULATOR (ICOS)) (HUMAN-MUS MUSCULUS MONOCLONAL GSK3359609 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL GSK3359609 .KAPPA.-CHAIN, DIMER
Systematic Name English
FELADILIMAB [JAN]
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS INDUCIBLE T-CELL COSTIMULATOR (ACTIVATION-INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE; CD278 ANTIGEN)); HUMANIZED MONOCLONAL ANTIBODY; .GAMMA.4 HEAVY CHAIN HUMANIZED (1-448) (VH (HOMO SAPIENS IGHV1-69*06 (85%
Common Name English
Feladilimab [WHO-DD]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C126804
Created by admin on Sat Dec 16 13:31:55 GMT 2023 , Edited by admin on Sat Dec 16 13:31:55 GMT 2023
PRIMARY
FDA UNII
OUP4QB2A3R
Created by admin on Sat Dec 16 13:31:55 GMT 2023 , Edited by admin on Sat Dec 16 13:31:55 GMT 2023
PRIMARY
CAS
2252518-85-5
Created by admin on Sat Dec 16 13:31:55 GMT 2023 , Edited by admin on Sat Dec 16 13:31:55 GMT 2023
PRIMARY
INN
11311
Created by admin on Sat Dec 16 13:31:55 GMT 2023 , Edited by admin on Sat Dec 16 13:31:55 GMT 2023
PRIMARY
USAN
JK-30
Created by admin on Sat Dec 16 13:31:55 GMT 2023 , Edited by admin on Sat Dec 16 13:31:55 GMT 2023
PRIMARY
From To
1_22 1_96
1_135 1_148
1_204 3_213
1_227 2_227
1_230 2_230
1_262 1_322
1_368 1_426
2_22 2_96
2_135 4_213
2_148 2_204
2_262 2_322
2_368 2_426
3_23 3_87
3_133 3_193
4_23 4_87
4_133 4_193
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_298
N 2_298
Related Record Type Details
TARGET -> AGONIST
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL