GLIAMILIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C23H33N5O5S
Molecular Weight	491.604
Optical Activity	( + / - )
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=NC=CC=C1C(=O)NCCC2CCN(CC2)S(=O)(=O)NC(=O)NC[C@@H]3C[C@H]4C[C@@H]3C=C4

InChI

InChIKey=MQQJZPWSYVPWPF-QYZOEREBSA-N

InChI=1S/C23H33N5O5S/c1-33-22-20(3-2-9-25-22)21(29)24-10-6-16-7-11-28(12-8-16)34(31,32)27-23(30)26-15-19-14-17-4-5-18(19)13-17/h2-5,9,16-19H,6-8,10-15H2,1H3,(H,24,29)(H2,26,27,30)/t17-,18+,19+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C23H33N5O5S
Molecular Weight	491.604
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/3037231 | https://www.ncbi.nlm.nih.gov/pubmed/1271411

Gliamilide is a high-potency sulfamylurea hypoglycemic agent. It has been found to be well tolerated in humans and displays a very short plasma half-life. Like sulfonylureas, gliamilide can lower blood glucose levels by increasing the insulin release from pancreatic beta cells.

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 08:20:13 GMT 2025` Edited by `admin` on `Wed Apr 02 08:20:13 GMT 2025`
Record UNII	OTY52EM5B2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLIAMILIDE

Official Name

English

CP-27,634

Preferred Name

English

3-PYRIDINECARBOXAMIDE, N-(2-(1-(((((BICYCLO(2.2.1)HEPT-5-EN-2-YLMETHYL)AMINO)CARBONYL)AMINO)SULFONYL)-4-PIPERIDINYL)ETHYL)-2-METHOXY-, ENDO

Common Name

English

gliamilide [INN]

Common Name

English

GLIAMILIDE [USAN]

Common Name

English

CP-27634

Code

English

ENDO-1-((4-(2-(2-METHOXYNICOTINAMIDO)ETHYL)PIPERIDINO)SULFONYL)-3-(5-NORBORNEN-2-YLMETHYL)UREA

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C97936