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Details

Stereochemistry ACHIRAL
Molecular Formula 2I.Pb
Molecular Weight 461.0
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEAD IODIDE

SMILES

[I-].[I-].[PbH2++]

InChI

InChIKey=CFAVEAYMIIKCJY-UHFFFAOYSA-L
InChI=1S/2HI.Pb.2H/h2*1H;;;/q;;+2;;/p-2

HIDE SMILES / InChI

Molecular Formula Pb
Molecular Weight 207.2
Charge 2
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula HI
Molecular Weight 127.9124
Charge 0
Count
MOL RATIO 2 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

There is no information about biological application only a few articles about pharmacological application of lead fluoride, that this substance was investigated for topical dental caries.

CNS Activity

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
It was investigated the cytotoxicity of lead chloride in vitro cultured lymphocytes from human umbilical cord blood, using four monitoring methods namely, trypan blue staining, acridine orange/ethidium bromide staining, 3-[4,5-dimethylthiazol-2-yl] 2,5-diphenyl tetrazolium bromide (MTT) and neutral red uptake assays; lead genotoxicity to lymphocytes was monitored by comet assay. The MIC value in each method was invariably 300 mg/L for PbCl2. Lethal concentration25 (LC25) values were almost in an agreeable range: 691.83 to 831.76 mg/L; LC50 values in each method were almost in the range: 1174.9 to 1348.9 mg/L; LC100 values were in the range: 3000 to 3300 mg/L, for lead chloride. The comet assay also indicated that the LC100 values were 3300 mg/L lead chloride. Thus, both cytotoxicity and genotoxicity were recorded at 3300 mg/L lead chloride with lymphocytes.
Substance Class Chemical
Record UNII
OTL90F2GLT
Record Status Validated (UNII)
Record Version