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Details

Stereochemistry RACEMIC
Molecular Formula C24H26FNO4
Molecular Weight 411.4659
Optical Activity ( + / - )
Defined Stereocenters 2 / 2
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of FLUVASTATIN ANTI-ISOMER

SMILES

CC(C)N1C(\C=C\[C@H](O)C[C@@H](O)CC(O)=O)=C(C2=C1C=CC=C2)C3=CC=C(F)C=C3

InChI

InChIKey=FJLGEFLZQAZZCD-FUTHQCHMSA-N
InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19+/m0/s1

HIDE SMILES / InChI

Molecular Formula C24H26FNO4
Molecular Weight 411.4659
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 1
Optical Activity UNSPECIFIED

Description
Curator's Comment: The description was created based on several sources, including https://www.jstage.jst.go.jp/article/dmpk1986/10/6/10_6_779/_pdf

Fluvastatin Anti-Isomer is a metabolite of lipid-lowering agent Fluvastatin. Fluvastatin is very unstable during storage and anti-isomer as well as lactones are the main formed by-products.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Improvement in chemical and physical stability of fluvastatin drug through hydrogen bonding interactions with different polymer matrices.
2009 Jan

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 05:33:28 GMT 2023
Edited
by admin
on Sat Dec 16 05:33:28 GMT 2023
Record UNII
OT7W70P7E1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FLUVASTATIN ANTI-ISOMER
Common Name English
(3RS,5RS,6E)-7-(3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL)-1H-INDOL-2-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID
Systematic Name English
6-HEPTENOIC ACID, 7-(3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL)-1H-INDOL-2-YL)-3,5-DIHYDROXY-, (3R,5R,6E)-REL-
Common Name English
FLUVASTATIN SODIUM IMPURITY A [EP IMPURITY]
Common Name English
Code System Code Type Description
FDA UNII
OT7W70P7E1
Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023
PRIMARY
CAS
174956-43-5
Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023
PRIMARY
EPA CompTox
DTXSID10169915
Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023
PRIMARY
PUBCHEM
9887837
Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023
PRIMARY
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