FLUVASTATIN ANTI-ISOMER

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H26FNO4
Molecular Weight	411.4659
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1C(\C=C\[C@H](O)C[C@@H](O)CC(O)=O)=C(C2=C1C=CC=C2)C3=CC=C(F)C=C3

InChI

InChIKey=FJLGEFLZQAZZCD-FUTHQCHMSA-N

InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+/t18-,19+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H26FNO4
Molecular Weight	411.4659
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19418962
Curator's Comment: The description was created based on several sources, including https://www.jstage.jst.go.jp/article/dmpk1986/10/6/10_6_779/_pdf

Fluvastatin Anti-Isomer is a metabolite of lipid-lowering agent Fluvastatin. Fluvastatin is very unstable during storage and anti-isomer as well as lactones are the main formed by-products.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:33:28 GMT 2023` Edited by `admin` on `Sat Dec 16 05:33:28 GMT 2023`
Record UNII	OT7W70P7E1
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FLUVASTATIN ANTI-ISOMER

Common Name

English

(3RS,5RS,6E)-7-(3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL)-1H-INDOL-2-YL)-3,5-DIHYDROXYHEPT-6-ENOIC ACID

Systematic Name

English

6-HEPTENOIC ACID, 7-(3-(4-FLUOROPHENYL)-1-(1-METHYLETHYL)-1H-INDOL-2-YL)-3,5-DIHYDROXY-, (3R,5R,6E)-REL-

Common Name

English

FLUVASTATIN SODIUM IMPURITY A [EP IMPURITY]

Common Name

English

Code System Code Type Description

FDA UNII

OT7W70P7E1

Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023

PRIMARY

CAS

174956-43-5

Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023

PRIMARY

EPA CompTox

DTXSID10169915

Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023

PRIMARY

PUBCHEM

9887837

Created by admin on Sat Dec 16 05:33:28 GMT 2023 , Edited by admin on Sat Dec 16 05:33:28 GMT 2023

PRIMARY

Related Record Type Details


					PYF7O1FV7F

FLUVASTATIN SODIUM

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Details

SMILES

InChI

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/19418962Curator's Comment: The description was created based on several sources, including https://www.jstage.jst.go.jp/article/dmpk1986/10/6/10_6_779/_pdf

Originator

Approval Year

Conditions

PubMed

Sample Use Guides

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19418962
Curator's Comment: The description was created based on several sources, including https://www.jstage.jst.go.jp/article/dmpk1986/10/6/10_6_779/_pdf