VADASTUXIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 10:30:26 GMT 2023` Edited by `admin` on `Sat Dec 16 10:30:26 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	MOUSE CHIMERIC
Sequence Type	COMPLETE
Record UNII	OQE503T586
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VADASTUXIMAB

Official Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD33 (SIALIC ACID BINDING IG-LIKE LECTIN 3, SIGLEC3, SIGLEC-3, GP67, P67)), CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-447) (MUS MUSCULUS VH (IGHV1- 85*01 -(IGHD) -IGHJ4*01) (8.8.10) (1-117) -HOMO SAPIE

Systematic Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN SIALIC ACID-BINDING IMMUNOGLOBULIN-LIKE LECTIN 3) (HUMAN-MUS MUSCULUS MONOCLONAL H2H12EC HEAVY CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL H2H12EC LIGHT CHAIN, DIMER

Systematic Name

English

VADASTUXIMAB [USAN]

Common Name

English

H2H12EC

Code

English

vadastuximab [INN]

Common Name

English

Code System Code Type Description

USAN

CD-155

Created by admin on Sat Dec 16 10:30:26 GMT 2023 , Edited by admin on Sat Dec 16 10:30:26 GMT 2023

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FDA UNII

OQE503T586

Created by admin on Sat Dec 16 10:30:26 GMT 2023 , Edited by admin on Sat Dec 16 10:30:26 GMT 2023

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NCI_THESAURUS

C152812

Created by admin on Sat Dec 16 10:30:26 GMT 2023 , Edited by admin on Sat Dec 16 10:30:26 GMT 2023

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INN

10242

Created by admin on Sat Dec 16 10:30:26 GMT 2023 , Edited by admin on Sat Dec 16 10:30:26 GMT 2023

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CAS

1436390-63-4

Created by admin on Sat Dec 16 10:30:26 GMT 2023 , Edited by admin on Sat Dec 16 10:30:26 GMT 2023

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From	To
1_22	1_96
1_144	1_200
1_261	1_321
1_367	1_425
2_22	2_96
2_144	2_200
2_261	2_321
2_367	2_425
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_220	3_214
2_220	4_214
1_226	2_226
1_229	2_229

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					HX0GZ7OLW5

MYELOID CELL SURFACE ANTIGEN CD33

TARGET -> INHIBITOR

Related Record Type Details


					OQE503T586

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL