LONAPEGSOMATROPIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 20:58:04 GMT 2025` Edited by `admin` on `Tue Apr 01 20:58:04 GMT 2025`
Protein Type	HORMONE
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	OP35X9610Y
Record Status	`Validated (UNII)`
Record Version

Download

Related Record	Type

Name

Type

Language

LONAPEGSOMATROPIN

Official Name

English

ACP-011

Preferred Name

English

POLY(OXY-1,2-ETHANEDIYL), .ALPHA.,.ALPHA.',.ALPHA.'',.ALPHA.'''-(((5-(4-((((3-(DIMETHYLAMINO)PROPYL)METHYLAMINO)CARBONYL)OXY)PHENYL)-5-(CARBOXYOXY)-1-OXOPENTYL)IMINO)BIS(6,1-HEXANEDIYLTHIO(2,5-DIOXO-3,1-PYRROLIDINEDIYL)(1-OXO-3,1-PROPANEDIYL)IMINO-3,1-PR

Systematic Name

English

TRANSCONPEG HGH

Code

English

LONAPEGSOMATROPIN [USAN]

Common Name

English

SOMATROPIN (GROWTH HORMONE) (HOMO SAPIENS) STATISTICALLY MONO SUBSTITUTED ON N6 OF LYSINE RESIDUES WITH THE RADICAL: ((1RS)-5-(BIS(6-(((3RS)-1-(3-((3-((2RS)-2,3-BIS(METHOXYPOLY(ETHYLENEOXY))PROPOXY)PROPYL)AMINO)-3-OXOPROPYL)-2,5-DIOXOPYRROLIDIN-3-YL)SULF

Systematic Name

English

Lonapegsomatropin [WHO-DD]

Common Name

English

RHGH-PEG

Code

English

lonapegsomatropin [INN]

Common Name

English

TRANSCONPEG-HGH

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

654718

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

Code System Code Type Description

RXCUI

2569562

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

PRIMARY

DAILYMED

OP35X9610Y

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

PRIMARY

SMS_ID

100000182982

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

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WIKIPEDIA

Lonapegsomatropin

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

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USAN

FG-115

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

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FDA UNII

OP35X9610Y

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

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NCI_THESAURUS

C174805

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

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CAS

1934255-39-6

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

PRIMARY

INN

10598

Created by admin on Tue Apr 01 20:58:04 GMT 2025 , Edited by admin on Tue Apr 01 20:58:04 GMT 2025

PRIMARY

From	To
1_53	1_165
1_182	1_189

Related Record Type Details

LONAPEGSOMATROPIN-TCGD

SUB_CONCEPT->SUBSTANCE

Amount:

Related Record Type Details


					OP35X9610Y

LONAPEGSOMATROPIN

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
PEGYLATION	[1_38] [1_41] [1_70] [1_140] [1_145] [1_158] [1_168] [1_172]	SITE_SPECIFIC		Amount:	LONAPEGSOMATROPIN MPEG 40000 LYSINE	CXA43H22OZ

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL