CENPLACEL-L

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 04:14:23 GMT 2025` Edited by `admin` on `Wed Apr 02 04:14:23 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	ALLOGENIC HUMAN
Source Materials State	LIVE
Source Materials Parent	`G0T704E6Z3` HOMO SAPIENS WHOLE
Part	placenta
Fraction Material Type	cells
Fraction Name	undifferentiated mesenchymal-like cells
Record UNII	OOH12XV6XR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CENPLACEL

Preferred Name

English

CENPLACEL-L

Official Name

English

ALLOGENEIC-UNRELATED PLACENTA-DERIVED STROMAL CELLS, EXPANDED EX VIVO

Common Name

English

PDA-001

Code

English

cenplacel [INN]

Common Name

English

HUMAN PLACENTA-DERIVED ADHERENT (PDA) CELLS THAT ARE CULTURE-EXPANDED, UNDIFFERENTIATED MESENCHYMAL-LIKE CELLS DERIVED FROM FULL-TERM PLACENTAL TISSUE. CELLULAR IDENTITY: MESENCHYMAL-LIKE STROMAL CELL: CD34-, CD10+, CD105+, AND CD200+.

Systematic Name

English

CENPLACEL-L [USAN]

Common Name

English

Code System Code Type Description

INN

10328

Created by admin on Wed Apr 02 04:14:23 GMT 2025 , Edited by admin on Wed Apr 02 04:14:23 GMT 2025

PRIMARY

USAN

DE-145

Created by admin on Wed Apr 02 04:14:23 GMT 2025 , Edited by admin on Wed Apr 02 04:14:23 GMT 2025

PRIMARY

NCI_THESAURUS

C171653

Created by admin on Wed Apr 02 04:14:23 GMT 2025 , Edited by admin on Wed Apr 02 04:14:23 GMT 2025

PRIMARY

SMS_ID

100000174584

Created by admin on Wed Apr 02 04:14:23 GMT 2025 , Edited by admin on Wed Apr 02 04:14:23 GMT 2025

PRIMARY

FDA UNII

OOH12XV6XR

Created by admin on Wed Apr 02 04:14:23 GMT 2025 , Edited by admin on Wed Apr 02 04:14:23 GMT 2025

PRIMARY

Related Record Type Details


					OOH12XV6XR

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID
	CD10+	IMMUNOLOGICAL
	CD34-	CELL SEPARATION
	CD105+	IMMUNOLOGICAL

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
ANTIGEN EXPRESSED	BIOLOGICAL		`UQ4V77A8VA` CD200
ANTIGEN NOT EXPRESSED	BIOLOGICAL		COSTIMULATORY MOLECULES (not present in database)
ANTIGEN NOT EXPRESSED	BIOLOGICAL		`PW3DO1LF7X` HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR (not present in database)
ANTIGEN NOT EXPRESSED	BIOLOGICAL		`ZWL6BH0E0S` HEMATOPOIETIC PROGENITOR CELL ANTIGEN CD34
ANTIGEN EXPRESSED	BIOLOGICAL		`1Y8Q34P575` ENDOGLIN
PLASTIC ADHERENT	BIOLOGICAL

ANTIGEN EXPRESSED	BIOLOGICAL		`MH8LWM8ARN` NEPRILYSIN
ANTIGEN NOT EXPRESSED	BIOLOGICAL		`E4ZK1AY5FU` HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A ALPHA CHAIN