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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H13FN2O7
Molecular Weight 292.2178
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of OGT-719

SMILES

OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@H]1O)N2C=C(F)C(=O)NC2=O

InChI

InChIKey=YHWGRVDTEORPPJ-WENHOLORSA-N
InChI=1S/C10H13FN2O7/c11-3-1-13(10(19)12-8(3)18)9-7(17)6(16)5(15)4(2-14)20-9/h1,4-7,9,14-17H,2H2,(H,12,18,19)/t4-,5+,6+,7-,9-/m1/s1

HIDE SMILES / InChI

Molecular Formula C10H13FN2O7
Molecular Weight 292.2178
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Bioavailability study of oral and intravenous OGT 719, a novel nucleoside analogue with preferential activity in the liver.
2001 Sep
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:38:01 GMT 2023
Edited
by admin
on Sat Dec 16 11:38:01 GMT 2023
Record UNII
OMZ81A5KDU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OGT-719
Code English
2,4(1H,3H)-PYRIMIDINEDIONE, 5-FLUORO-1-.BETA.-D-GALACTOPYRANOSYL-
Common Name English
5-FLUORO-1-.BETA.-D-GALACTOPYRANOSYL-2,4(1H,3H)-PYRIMIDINEDIONE
Common Name English
OGT 719
Code English
Code System Code Type Description
EPA CompTox
DTXSID501031291
Created by admin on Sat Dec 16 11:38:01 GMT 2023 , Edited by admin on Sat Dec 16 11:38:01 GMT 2023
PRIMARY
FDA UNII
OMZ81A5KDU
Created by admin on Sat Dec 16 11:38:01 GMT 2023 , Edited by admin on Sat Dec 16 11:38:01 GMT 2023
PRIMARY
WEB RESOURCE
OGT-719
Created by admin on Sat Dec 16 11:38:01 GMT 2023 , Edited by admin on Sat Dec 16 11:38:01 GMT 2023
PRIMARY OGT 719 (Oxford GlycoSciences, Abingdon, UK) is a novel nucleoside analogue with a galactose molecule attached to a fluorinated pyrimidine. OGT 719 has the capacity selectively to bind to asialoglycoprotein receptors that are found exclusively on hepatocytes and hepatocellular carcinoma (HCC) cells.
CAS
185843-61-2
Created by admin on Sat Dec 16 11:38:01 GMT 2023 , Edited by admin on Sat Dec 16 11:38:01 GMT 2023
PRIMARY
PUBCHEM
9838997
Created by admin on Sat Dec 16 11:38:01 GMT 2023 , Edited by admin on Sat Dec 16 11:38:01 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY