TRENONACOG ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:09:37 GMT 2025` Edited by `admin` on `Mon Mar 31 21:09:37 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	OMD1OJM5L7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TRENONACOG ALFA

Official Name

English

trenonacog alfa [INN]

Preferred Name

English

BLOOD-COAGULATION FACTOR IX (148-THREONINE) (SYNTHETIC HUMAN ISOFORM IB1001)

Common Name

English

human coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), 148-threonine variant, produced in Chinese Hamster Ovary (CHO) cells (alfa glycoform)

Common Name

English

TRENONACOG ALFA [USAN]

Common Name

English

Trenonacog alfa [WHO-DD]

Common Name

English

IB1001

Code

English

IB-1001

Code

English

Classification Tree Code System Code

WHO-VATC

QB02BD12

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

WHO-ATC

B02BD12

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

NCI_THESAURUS

C82270

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C152727

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

FDA UNII

OMD1OJM5L7

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

DRUG BANK

DB13201

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

ChEMBL

CHEMBL3039538

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

INN

9455

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

CAS

1232401-60-3

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

EVMPD

SUB128553

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

ALTERNATIVE

SMS_ID

100000138107

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

EVMPD

SUB77428

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

USAN

YY-108

Created by admin on Mon Mar 31 21:09:37 GMT 2025 , Edited by admin on Mon Mar 31 21:09:37 GMT 2025

PRIMARY

From	To
1_18	1_23
1_51	1_62
1_56	1_71
1_73	1_82
1_88	1_99
1_95	1_109
1_111	1_124
1_132	1_289
1_206	1_222
1_336	1_350
1_361	1_389

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_157
N	1_167

Related Record Type Details


					OMD1OJM5L7

TRENONACOG ALFA

ACTIVE MOIETY

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_7] [1_8] [1_15] [1_17] [1_20] [1_21] [1_26] [1_27] [1_30] [1_33] [1_36] [1_40]		E		.GAMMA.-CARBOXYGLUTAMIC ACID	16FQV4RZKL

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL