U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H7NO3.Al.Ca
Molecular Weight 220.195
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 5

SHOW SMILES / InChI
Structure of AMINOSALICYLATE CALCIUM ALUMINIUM

SMILES

[Al+3].[Ca++].NC1=CC(O)=C(C=C1)C(O)=O

InChI

InChIKey=LSJVUFUCZLYWIC-UHFFFAOYSA-N
InChI=1S/C7H7NO3.Al.Ca/c8-4-1-2-5(7(10)11)6(9)3-4;;/h1-3,9H,8H2,(H,10,11);;/q;+3;+2

HIDE SMILES / InChI

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Al
Molecular Weight 26.9815
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C7H5NO3
Molecular Weight 151.1195
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Aluminoparaaminosalicylate calcium hydrate is antimicrobial agents and anti-inflammatory agent for topical and oral use. Para-aminosalicylic acid is an active component of Aluminoparaaminosalicylate calcium. Para-aminosalicylic acid has been shown to be a pro-drug and it is incorporated into the folate pathway by dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate a hydroxyl dihydrofolate antimetabolite, which in turn inhibits dihydrofolate reductase (DHFR) enzymatic activity.

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 08:07:03 GMT 2023
Edited
by admin
on Sat Dec 16 08:07:03 GMT 2023
Record UNII
OL3A7UIY47
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMINOSALICYLATE CALCIUM ALUMINIUM
WHO-DD  
Common Name English
ALUMINUM CALCIUM P-AMINOSALICYLATE
Common Name English
SALICYLIC ACID, 4-AMINO-, ALUMINUM CALCIUM SALT
Common Name English
BENZOIC ACID, 4-AMINO-2-HYDROXY-, ALUMINUM CALCIUM SALT (1:?:?)
Systematic Name English
BENZOIC ACID, 4-AMINO-2-HYDROXY-, ALUMINUM CALCIUM SALT
Common Name English
Aminosalicylate calcium aluminium [WHO-DD]
Common Name English
Code System Code Type Description
CAS
28041-93-2
Created by admin on Sat Dec 16 08:07:03 GMT 2023 , Edited by admin on Sat Dec 16 08:07:03 GMT 2023
PRIMARY
FDA UNII
OL3A7UIY47
Created by admin on Sat Dec 16 08:07:03 GMT 2023 , Edited by admin on Sat Dec 16 08:07:03 GMT 2023
PRIMARY
PUBCHEM
164512939
Created by admin on Sat Dec 16 08:07:03 GMT 2023 , Edited by admin on Sat Dec 16 08:07:03 GMT 2023
PRIMARY
EVMPD
SUB12860MIG
Created by admin on Sat Dec 16 08:07:03 GMT 2023 , Edited by admin on Sat Dec 16 08:07:03 GMT 2023
PRIMARY